一磷酸硫胺氯化物二水合物，Thiamine monophosphate chloride dihydrate；EMPROVE® API

图片 一磷酸硫胺氯化物二水合物，Thiamine monophosphate chloride dihydrate；EMPROVE® API
别名：氯化亚氨基磷酸酯；TMP氯化物二水合物；Aneurine monophosphate chloride； Empirical Formula (Hill Notation): C12H18ClN4O4PS · 2H2O CAS号: 273724-21-3 分子量: 416.82 Beilstein: 3844977 MDL编号: MFCD00063473 EC索引号: 208-536-9
制造商品牌: SAFC , 默克 Merck , 西格玛 Sigma-Aldrich
货号（SKU）: 5.00667
CAS号: 273724-21-3
MDL号: MFCD00063473
签订合同 √ 正规发票 √ 技术支持 √ 质量保障 √ 全程可追溯 √
¥12,300.00

说明

一般描述

We provide industry-leading production know-how and comprehensive regulatory support for high-quality APIs, backed by nearly 200 years of experience. From a complete portfolio of innovative folates to custom synthesis, our customized and scalable solutions meet your specific production needs. As part of our EMPROVE® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.
 

应用

Thiamine phosphoric acid ester chloride dihydrate is a source for Vitamin B1 for use in clinical nutrition, vitamin supplements and infusion for Vitamin B1 deficiency. Thiamine phosphoric acid ester chloride dihydrate Emprove® API is manufactured according to ICH Q7 guidelines. An ASMF is available.
This product is part of our proprietary Viscosity Reduction Platform and suitable for highly concentrated protein-based formulations.
 

法律信息

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany
 
 

属性

蒸汽压

<1 Pa ( 50 °C)

质量水平

600

产品线

EMPROVE® API

形式

solid

pH值（酸碱度）

2-3 (20 °C, 100 g/L in H2O)

mp

135 °C (decomposition)

溶解性

176 g/L

密度

1.53 g/cm3 at 20 °C

堆积密度

670 kg/m3

application(s)

liquid formulation
pharmaceutical
semi-solid formulation
solid formulation

储存温度

2-25°C

SMILES string

[Cl-].Cc1ncc(C[n+]2csc(CCOP(O)(O)=O)c2C)c(N)n1

InChI

1S/C12H17N4O4PS.ClH/c1-8-11(3-4-20-21(17,18)19)22-7-16(8)6-10-5-14-9(2)15-12(10)13;/h5,7H,3-4,6H2,1-2H3,(H3-,13,14,15,17,18,19);1H

InChI key

GUGWNSHJDUEHNJ-UHFFFAOYSA-N

 

安全信息

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H317

危险分类

Skin Sens. 1

储存分类代码

11 - Combustible Solids

WGK

WGK 1

个人防护装备

Eyeshields, Gloves, type N95 (US)

商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 30 | 欧洲Eur. ≥ 10 | 東京Tokyo ≥ 9 | 香港与北京 ≥ 30
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