Catalogue Number | C725000 |
Chemical Name | S-(-)-Cotinine |
Synonyms | (5S)-1-Methyl-5-(3-pyridinyl)-2-pyrrolidinone; (S)-(-)-1-Methyl-5-(3-pyridiyl)-2- pyrrolidinone; (-)-Cotinine; (S)-Cotinine; NIH 10498; |
CAS Number | 486-56-6 |
Molecular Formula: | C10H12N2O |
Appearance | Colourless to Very Dark Orange Oil to Solid |
Molecular Weight | 176.22 |
Storage | Hygroscopic, Refrigerator, Under inert atmosphere |
Solubility | Chloroform (Sparingly), DMSO (Slightly), Methanol (Sparingly) |
Stability | Hygroscopic |
Category | Standards; Stimulant; Nicotine Derivatives and Metabolites; |
Boiling Point | 145 - 150°C/3 mm |
Applications | S-(-)-Cotinine is a major metabolite of Nicotine (N412450) in humans. It is a carcinogen. This compound is a contaminant of emerging concern (CECs) |
References | Thompson, J.A., et al.: J. Chromatog., 231, 53 (1982); Seeman, J.I., et al.: J. Org. Chem., 51, 1548 (1986); Nakajima, M., et al.: Drug Metab. Dispos., 24, 1212 (1996) |