信号通路, 信号转导, Cell Signaling

别名：布帕西布盐酸盐；5-[2,6-Di(4-morpholinyl)-4-pyrimidinyl]-4-(trifluoromethyl)-2-pyridinamine

CAS：1312445-63-8；分子式：C18H22ClF3N6O2；分子量：446.85

别名：5-[2,6-二(4-吗啉基)-4-嘧啶基]-4-(三氟甲基)-2-吡啶胺；5-[2,6-Di(4-morpholinyl)-4-pyrimidinyl]-4-(trifluoromethyl)-2-pyridinamine；BKM-120

CAS：944396-07-0；分子式：C18H21F3N6O2；分子量：410.39

别名：8-Chloro-2-phenyl-3-[(1S)-1-(9H-purin-6-ylamino)ethyl]-1(2H)-isoquinolinone；(S)-3-(1-((9H-嘌呤-6-基)氨基)乙基)-8-氯-2-苯基-1(2H)-异喹啉酮

CasNo：1201438-56-3；MDL：MFCD15144635；分子式：C22H17ClN6O；分子量：416.86

别名；GDC0941；Pictrelisib；2-(1H-吲唑-4-基)-6-(4-甲磺酰哌嗪-1-基甲基)-4-吗啉-4-基-噻吩并[3,2-d]嘧啶；2-(1H-Indazol-4-yl)-6-(4-methylsulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2- d]pyrimidine；4-(2-(1H-Indazol-4-yl)-6-((4-(methylsulfonyl)piperazin-1-yl)methyl)thieno[3,2-d]pyrimidin-4-yl)morpholine；2-(1H-吲唑-4-基)-6-(4-甲烷磺酰基哌嗪-1-基甲基)-4-吗啉-4-基-噻吩并[3,2-d]嘧

Empirical Formula (Hill Notation): C23H27N7O3S2 CAS号: 957054-30-7 分子量: 513.64

别名：苹果酸卡博替尼；XL184；Cabozantinib S-malate；N-(4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide (S)-2-hydroxysuccinate；N-(4-((6,7-二甲氧基喹啉-4-基)氧基)苯基)-N-(4-氟苯基)环丙烷-1,1-二甲酰胺(S)-2-羟基丁二酸盐

CAS：1140909-48-3；分子式：C32H30FN3O10；分子量：635.60

别名：KRN-633；N-[2-Chloro-4-[(6,7-dimethoxy-4-quinazolinyl)oxy]phenyl]-N′-propyl-urea；N-[2-氯-4-[(6,7-二甲氧基-4-喹唑啉基)氧基]苯基]-N'-丙基脲

Empirical Formula (Hill Notation): C20H21ClN4O4 CAS号: 286370-15-8 分子量: 416.86 NACRES: NA.77

别名：N-(2,4-Difluorophenyl)-Nʹ-(4-(6,7-dimethoxy-4-quinolyloxy)-2-fluorophenyl)urea, Vascular Endothelial Growth Factor Receptor 2 Kinase Inhibitor VI, VEGFR Tyrosine Kinase Inhibitor XXIV, VEGFR2 Kinase Inhibitor VI, 1-(2,4-二氟苯基)-3-(4-((6,7-二甲氧基喹啉-4-基)氧基)-2-氟苯基)脲

Empirical Formula (Hill Notation): C24H18F3N3O4 CAS号: 228559-41-9 分子量: 469.41

别名：BAW2881；6-((2-氨基-4-嘧啶基)氧基)-N-(3-(三氟甲基)苯基)-1-萘甲酰胺；6-((2-aminopyrimidin-4-yl)oxy)-N-(3-(trifluoromethyl)phenyl)-1-naphthamide

CAS：861875-60-7；分子式：C22H15F3N4O2；分子量：424.38

别名：TGF-β RI 激酶抑制剂 IV；ALK4、5和7激酶抑制剂；A-83-01；A83-01；3-(6-甲基-2-吡啶基)-N-苯基-4-(4-喹啉基)-1H-吡唑-1-硫代甲酰胺；3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide

Empirical Formula (Hill Notation): C25H19N5S CAS号: 909910-43-6 分子量: 421.52 NACRES: NA.77

别名：PF-06463922；PF-6463922；(10R)-7-氨基-12-氟-2,10,16-三甲基-15-氧代-10,15,16,17-四氢-2H.8,4-(甲基)吡唑并[4,3.h ] [2,5,11]-苯并二氮杂二环十四癸-3-甲腈；(10R)-7-Amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2H.8,4-(metheno)pyrazolo[4,3.h][2,5,11]-benzoxadiazacyclotetradecine-3-carbonitrile

Empirical Formula (Hill Notation): C21H19FN6O2 CAS号: 1924207-18-0 分子量: 406.41 MDL编号: MFCD28144520

别名：醋酸洛拉替尼；罗拉替尼乙酸盐；PF-06463922；PF-6463922；(10R).7-氨基-12-氟-2,10,16-三甲基-15-氧代-10,15,16,17-四氢-2H.8,4-(甲基)吡唑并[4,3.h ] [2,5,11]-苯并二氮杂二环十四癸-3-乙酸乙腈；(10R).7-Amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2H.8,4-(metheno)pyrazolo[4,3.h][2,5,11]-benzoxadiazacyclotetradecine-3-carbonitrile acetate, Lorlatinib acetate

Empirical Formula (Hill Notation): C21H19FN6O2 · CH3COOH CAS号: 1924207-18-0 分子量: 466.46 PubChem化学物质编号: 329823805 NACRES: NA.77

别名：3-[6-[[4-(三氟甲氧基)苯基]氨基]-4-嘧啶基]苯甲酰胺；Bcr-abl Inhibitor；3-[6-[[4-(Trifluoromethoxy)phenyl]amino]-4-pyrimidinyl]benzamide

Empirical Formula (Hill Notation): C18H13F3N4O2 CAS号: 778270-11-4 分子量: 374.32 MDL编号: MFCD09265253 PubChem化学物质编号: 24724498 NACRES: NA.77