信号通路, 信号转导, Cell Signaling

20,000多种特异性抑制剂、激动剂作用于表观遗传学、PI3K/Akt/mTOR、凋亡、MAPK、Wnt等20多个信号通路的375个靶点蛋白,覆盖癌症、神经科学、免疫学等热门疾病研究领域。BSZH北实纵横科学公司的50多种活性化合物库,包含10,000多种具有生物活性的小分子化合物,可用于高通量筛选 (HTS)和高内涵筛选 (HCS),是进行新药筛选和新适应症发现等研究的专业工具。

浏览为
排序由
显示 每页

PF-4191834,≥98% (HPLC)

PZ0360
别名:PF 4191834;4-(3-(4-(1-甲基-1H-吡唑-5-基)苯基)-四氢-2H-吡喃-4-甲酰胺;四氢-4-[[[4-(1-甲基-1H-吡唑-5-基)苯基]硫代]苯基]-2H-吡喃-4-甲酰胺;4-(3-(4-(1-Methyl-1H-pyrazol-5-yl) phenylthio) phenyl)-tetrahydro-2H-pyran-4-carboxamide, Tetrahydro-4-[3-[[4-(1-methyl-1H-pyrazol-5-yl)phenyl]thio]phenyl]-2H-pyran-4-carboxamide;PF4191834

Empirical Formula (Hill Notation): C22H23N3O2S CAS号: 1029317-21-2 分子量: 393.50 MDL编号: MFCD18382581 NACRES: NA.77
¥1,829.67

PF5274857盐酸盐,PF-5274857 hydrochloride;≥98% (HPLC)

PZ0217
别名:1-[4-(5′-Chloro-3,5-dimethyl-2,4′-bipyridin-2′-yl)piperazin-1-yl] -3- (methylsulfonyl)propan-1-one hydrochloride;1-[4-(5'-氯-3,5-二甲基[2,4'-联吡啶]-2'-基)-1-哌嗪基]-3-(甲基磺酰基)-1-丙酮

Empirical Formula (Hill Notation): C20H25ClN4O3S · HCl CAS号: 1373615-35-0 (free base) 分子量: 473.42 MDL编号: MFCD24387542 PubChem化学物质编号: 329823776 NACRES: NA.77
¥1,950.00

PF543盐酸盐,PF-543 hydrochloride;≥98% (HPLC)

PZ0234
别名:(R)-(1-(4-((3-甲基-5-(苯磺酰基甲基)苯氧基)甲基)苄基)吡咯烷-2-基)甲醇盐酸盐, (2R)-1-[[[4-[[3-甲基-5-[(苯磺酰基)甲基]苯氧基]甲基]苯基]甲基] -2-吡咯烷甲醇 盐酸盐, PF-05144543盐酸盐;PF05144543 hydrochloride, (R)-(1-(4-((3-Methyl-5-(phenylsulfonylmethyl)phenoxy)methyl)benzyl)pyrrolidin-2-yl)methanol hydrochloride, (2R)-1-[[4-[[3-Methyl-5-[(phenylsulfonyl)methyl]phenoxy]methyl]phenyl]methyl]-2-pyrrolidinemethanol hydrochloride

Empirical Formula (Hill Notation): C27H31NO4S · HCl CAS号: 1415562-82-1 (free base) 分子量: 502.07 MDL编号: MFCD28411614 PubChem化学物质编号: 329823785 NACRES: NA.77
¥1,652.60

PF-6274484,≥98% (HPLC)

PZ0342
别名:PF6274484;N-[4-[(3-氯-4-氟苯基)氨基]-7-甲氧基-6-喹唑啉基]-2-丙烯酰胺;N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-2-propenamide

Empirical Formula (Hill Notation): C18H14ClFN4O2 CAS号: 1035638-91-5 分子量: 372.78 MDL编号: MFCD30182370 PubChem化学物质编号: 329823851
¥1,391.58

PF956980水合物,PF-956980 hydrate;≥98% (HPLC)

PZ0151
别名:4-甲基-3-[甲基-(7H-吡咯并[2,3-d]嘧啶-4-基)氨基]-哌啶-1-基}-吡咯烷-1-基甲酮水合物;{(3R,4R)-4-Methyl-3-[methyl-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amino]-piperidin-1-yl}-pyrrolidin-1-yl-methanone hydrate

Empirical Formula (Hill Notation): C18H26N6O · xH2O 分子量: 342.44 (anhydrous basis) MDL编号: MFCD18452852 PubChem化学物质编号: 329823736 NACRES: NA.77
¥1,889.90

PF-998425,≥98% (HPLC)

PZ0131
别名:PF998425;4-((1R,2R)-2-羟基环己基)-2(三氟甲基)苄腈;4-((1R,2R)-2-Hydroxycyclohexyl)-2(trifluoromethyl)benzonitrile

Empirical Formula (Hill Notation): C14H14F3NO CAS号: 1076225-27-8 分子量: 269.26 MDL编号: MFCD17215970 PubChem化学物质编号: 329823718 NACRES: NA.77
¥1,941.33

PF-CBP1 [ISOX INACT],≥98% (HPLC)

PZ0325
别名:4-(2-(5-(3,5-二甲基异恶唑-4-基)-2-(4-丙氧基苯乙基)-1H-苯并咪唑-1-基)乙基吗啉;5-(二甲基-1,2-恶唑-4-基)-1-[2-(吗啉-4-基)乙基]-2-[2-(4-丙氧基苯基)乙基]-1H-1,3-苯并二唑;4-(2-(5-(3,5-Dimethylisoxazol-4-yl)-2-(4-propoxyphenethyl)-1H-benzo[d]imidazol-1-yl)ethyl)morpholine, PF-06670910, PF CBP1, 5-(Dimethyl-1,2-oxazol-4-yl)-1-[2-(morpholin-4-yl)ethyl]-2-[2-(4-propoxyphenyl)ethyl]-1H-1,3-benzodiazole

Empirical Formula (Hill Notation): C29H36N4O3 分子量: 488.62 NACRES: NA.77
¥1,591.58

PF06691283,≥98% (HPLC)

PZ0260
别名:PF-06691283;(4S,4aR,6R,8aS)-8a-(2,4-二氟苯基)-4-氟甲基-6-(4-甲基恶唑-2-基)-4,4a,5,6,8,8a-六氢-7-氧杂-3-硫杂-1-氮杂-2-萘胺;(4S,4aR,6R,8aS)-8a-(2,4-Difluoro-phenyl)-4-fluoromethyl-6-(4-methyl-oxazol-2-yl)-4,4a,5,6,8,8a-hexahydro-7-oxa-3-thia-1-aza-naphthalen-2-ylamine

Empirical Formula (Hill Notation): C18H18F3N3O2S 分子量: 397.41 MDL编号: MFCD28580117 PubChem化学物质编号: 329823796
¥4,750.00

PFI-4,≥98% (HPLC)

PZ0307
别名:PF-05363047;N-(1,3-二甲基-2-氧代-6-吡咯烷-1-基苯并咪唑-5-基)-2-甲氧基苯甲酰胺;N-[2,3-二氢-1,3-二甲基-2-氧代-6-(1-吡咯烷基)-1H-苯并咪唑-5-基]-2-甲氧基苯甲酰胺;N-(1,3-Dimethyl-2-oxo-6-pyrrolidin-1-ylbenzimidazol-5-yl)-2-methoxybenzamide;N-[2,3-Dihydro-1,3-dimethyl-2-oxo-6-(1-pyrrolidinyl)-1H-benzimidazol-5-yl]-2-methoxy-benzamide

Empirical Formula (Hill Notation): C21H24N4O3 CAS号: 900305-37-5 分子量: 380.44 PubChem化学物质编号: 329823828 NACRES: NA.77
¥1,591.58

PHA-408,≥98% (HPLC)

PZ0266
别名:PHA408;PHA-00767408, PHA-767408, 8-(5-氯-2-(4-甲基哌嗪-1-基)异烟酰胺基)-1-(4-氟苯基)-4,5,二氢-1H-苯并[g]吲唑-3-甲酰胺;8-(5-Chloro-2-(4-methylpiperazin-1-yl)isonicotinamido)-1-(4-fluorophenyl)-4,5,dihydro-1H-benzo[g]indazole-3-carboxamide

Empirical Formula (Hill Notation): C29H27ClFN7O2 CAS号: 503555-55-3 分子量: 560.02
¥1,591.58

盐酸喹那普利,Quinapril hydrochloride;≥98% (HPLC), solid

Q0632
别名:喹那普利盐酸盐;(3S)-2-[(2S)-2-[[(1S)-1-乙氧基羰基-3-苯基丙基]氨基]-1-氧代丙基]-1,2,3,4-四氢-3-异喹啉羧酸盐酸盐;(3S)-2-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid hydrochloride

Empirical Formula (Hill Notation): C25H30N2O5 · HCl CAS号: 82586-55-8 分子量: 474.98 MDL编号: MFCD00889215 PubChem化学物质编号: 329823858 NACRES: NA.77
¥7,763.10

盐酸喹那普利,Quinapril hydrochloride;Pharmaceutical Secondary Standard; Certified Reference Material

PHR1944
别名:盐酸喹那普利标准品;喹那普利盐酸盐;(3S)-2-[(2S)-2-[[(1S)-1-乙氧基羰基-3-苯基丙基]氨基]-1-氧代丙基]-1,2,3,4-四氢-3-异喹啉羧酸盐酸盐;(3S)-2-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid hydrochloride

Empirical Formula (Hill Notation): C25H30N2O5 · HCl CAS号: 82586-55-8 分子量: 474.98 MDL编号: MFCD00889215 PubChem化学物质编号: 329823858 NACRES: NA.77
¥2,448.74