PF-CBP1 [ISOX INACT]，≥98% (HPLC)

图片 PF-CBP1 [ISOX INACT]，≥98% (HPLC)
别名：4-(2-(5-(3,5-二甲基异恶唑-4-基)-2-(4-丙氧基苯乙基)-1H-苯并咪唑-1-基)乙基吗啉；5-（二甲基-1，2-恶唑-4-基）-1-[2-（吗啉-4-基）乙基]-2-[2-（4-丙氧基苯基）乙基]-1H-1，3-苯并二唑；4-(2-(5-(3,5-Dimethylisoxazol-4-yl)-2-(4-propoxyphenethyl)-1H-benzo[d]imidazol-1-yl)ethyl)morpholine, PF-06670910, PF CBP1, 5-(Dimethyl-1,2-oxazol-4-yl)-1-[2-(morpholin-4-yl)ethyl]-2-[2-(4-propoxyphenyl)ethyl]-1H-1,3-benzodiazole

Empirical Formula (Hill Notation): C29H36N4O3 分子量: 488.62 NACRES: NA.77
制造商品牌: 西格玛 Sigma-Aldrich
货号（SKU）: PZ0325
CAS号: 1962928-21-7
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¥1,591.58

说明

一般描述

The gene CBP (CREB binding protein) is mapped to human chromosome 16p13.[1]
 

生化/生理作用

CBP is a transcriptional coactivator. The protein is a link between the DNA-associated transcription factors and the RNA polymerase 2 complex. It also exhibits histone acetyltransferase activity.[2]
PF-CBP1 is potent and highly-selective inhibitor of the bromodomain of CREB binding protein (CBP BRD) that down regulates targets of CBP in macrophages primary neurons. Also, PF-CBP1 significantly reduces levels of RGS4 mRNA levels in neurons.
 

其他说明

This compound was developed by Pfizer for Gene Regulation research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.
 

法律信息

Sold for research purposes under agreement from Pfizer Inc.
Pfizer is a registered trademark of Pfizer, Inc.
 
 

属性

质量水平

100

检测方案

≥98% (HPLC)

形式

powder

manufacturer/tradename

Pfizer®

颜色

white to beige

溶解性

DMSO: 20 mg/mL, clear

创始人

Pfizer

储存温度

room temp

 

安全信息

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

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储存温度 Storage temp.常温阴凉避光
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