生物活性小分子, Small Molecules
包含多种强效选择性探针,可调节所有通路和主要靶标类别的靶标活性;可为您的神经科学、基因调控、ADME/Tox、免疫学、离子通道和脂质信号传导、细胞凋亡和细胞周期、细胞因子和生长因子药物发现工作流程提供支持。
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PF-06281355 [PF-1355],≥98% (HPLC)
PZ0277
别名:PF06281355;6-(2,5-二甲氧基苯基)-3,4-二氢-4-氧代-2-硫代-1(2H)-嘧啶乙酰胺;6-(2,5-Dimethoxyphenyl)-3,4-dihydro-4-oxo-2-thioxo-1(2H)-pyrimidineacetamide, PF 6281355
Empirical Formula (Hill Notation): C14H15N3O4S CAS号: 1435467-38-1 分子量: 321.35 NACRES: NA.77
Empirical Formula (Hill Notation): C14H15N3O4S CAS号: 1435467-38-1 分子量: 321.35 NACRES: NA.77
¥1,591.58
PF-06284674,≥98% (HPLC)
PZ0301
别名:PF06284674;2-(1H-苯并咪唑-1-基甲基)-6-甲基-4H-吡啶并[1,2-a]嘧啶-4-酮;2-(1H-Benzimidazol-1-ylmethyl)-6-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
Empirical Formula (Hill Notation): C17H14N4O CAS号: 1434288-24-0 分子量: 290.32 MDL编号: MFCD29037211 PubChem化学物质编号: 329823823 NACRES: NA.77
Empirical Formula (Hill Notation): C17H14N4O CAS号: 1434288-24-0 分子量: 290.32 MDL编号: MFCD29037211 PubChem化学物质编号: 329823823 NACRES: NA.77
¥1,391.58
PF-06291874,≥98% (HPLC)
PZ0356
别名:PF06291874;N-[4-[(1S)-1-[3,5-Dimethyl-4-[4-(trifluoromethyl)-1H-pyrazol-1-yl]phenoxy]butyl]benzoyl]--alanine;N-[4-[(1S)-1-[3,5-二甲基-4-[4-(三氟甲基)-1H-吡唑-1-基]苯氧基]丁基]苯甲酰基]-丙氨酸
Empirical Formula (Hill Notation): C26H28F3N3O4 CAS号: 1393124-08-7 分子量: 503.51 MDL编号: MFCD30343861
Empirical Formula (Hill Notation): C26H28F3N3O4 CAS号: 1393124-08-7 分子量: 503.51 MDL编号: MFCD30343861
¥1,591.58
PF-06297470,≥98% (HPLC)
PZ0219
别名:PF06297470;1-甲基-3-(4-甲基-3-吡啶基)-6-(2-吡啶基甲氧基)-1H-吡唑并[3,4-b]吡嗪;1-Methyl-3-(4-methyl-3-pyridinyl)-6-(2-pyridinylmethoxy)-1H-pyrazolo[3,4-b]pyrazine
Empirical Formula (Hill Notation): C18H16N6O CAS号: 1539296-45-1 分子量: 332.36 MDL编号: MFCD28100803 PubChem化学物质编号: 329823777
Empirical Formula (Hill Notation): C18H16N6O CAS号: 1539296-45-1 分子量: 332.36 MDL编号: MFCD28100803 PubChem化学物质编号: 329823777
¥1,591.58
PF06305591二水合物,PF-06305591 dihydrate;≥98% (HPLC)
PZ0297
别名:αR, βS-β-氨基-6-(1,1-二甲基乙基)-α-甲基-1H-苯并咪唑-2-丙酰胺二水合物;(αR,βS)-β-Amino-6-(1,1-dimethylethyl)-α-methyl-1H-benzimidazole-2-propanamide dihydrate
Empirical Formula (Hill Notation): C15H22N4O · 2H2O CAS号: 1449473-97-5 (anhydrous) 分子量: 310.39 PubChem化学物质编号: 329823820 NACRES: NA.77
Empirical Formula (Hill Notation): C15H22N4O · 2H2O CAS号: 1449473-97-5 (anhydrous) 分子量: 310.39 PubChem化学物质编号: 329823820 NACRES: NA.77
¥1,591.58
PF06412154盐酸盐,PF-06412154 hydrochloride;≥98% (HPLC)
PZ0333
别名:N-[4-[(1R)-1-[(3-甲基-2-喹啉基)氨基]丁基]苯甲酰基]-β-丙氨酸盐酸盐;N-[4-[(1R)-1-[(3-Methyl-2-quinolinyl)amino]butyl]benzoyl]-β-alanine hydrochloride
Empirical Formula (Hill Notation): C24H27N3O3 · HCl CAS号: 1421349-19-0 分子量: 441.95 PubChem化学物质编号: 329823844
Empirical Formula (Hill Notation): C24H27N3O3 · HCl CAS号: 1421349-19-0 分子量: 441.95 PubChem化学物质编号: 329823844
¥1,591.58
PF-06412562,≥98% (HPLC)
PZ0357
别名:PF06412562;4-[4-(4,6-二甲基-5-嘧啶基)-3-甲基苯氧基]-1H-吡唑并[4,3-c]吡啶;4-[4-(4,6-二甲基嘧啶-5-基)-3-甲基苯氧基]-1H-吡唑并[4,3-c]吡啶;4-[4-(4,6-Dimethyl-5-pyrimidinyl)-3-methylphenoxy]-1H-pyrazolo[4,3-c]pyridine, PF 06412562, PF06412562, 4-[4-(4,6-Dimethylpyrimidin-5-yl)-3-methylphenoxy]-1H-pyrazolo[4,3-c]pyridine
Empirical Formula (Hill Notation): C19H17N5O CAS号: 1609258-91-4 分子量: 331.37
Empirical Formula (Hill Notation): C19H17N5O CAS号: 1609258-91-4 分子量: 331.37
¥1,591.58
PF-06422913,≥98% (HPLC)
PZ0334
别名:1-甲基-6-(2-吡啶甲氧基)-3-[4-三氟甲基-3-吡啶基]-1H-吡唑并[3,4-b]哌嗪;1-Methyl-6-(2-pyridinylmethoxy)-3-[4-(trifluoromethyl)-3-pyridinyl]-1H-pyrazolo[3,4-b]prazine, PF06422913;PF06422913
Empirical Formula (Hill Notation): C18H13F3N6O CAS号: 1539296-46-2 分子量: 386.33 PubChem化学物质编号: 329823845
Empirical Formula (Hill Notation): C18H13F3N6O CAS号: 1539296-46-2 分子量: 386.33 PubChem化学物质编号: 329823845
¥1,591.58
PF06439015甲磺酸盐,PF-06439015 methanesulfonate salt;≥98% (HPLC)
PZ0221
别名:PF-06439015 mesylate;2R-(5-{6-氨基-5-[1R-(5-氟-2-[1,2,3]三唑-2-基苯基)乙氧基]-吡啶-3-基}-4-甲基噻唑-2-基)-丙烷-1,2-二醇甲磺酸酯;2R-(5-{6-Amino-5-[1R-(5-fluoro-2-[1,2,3]triazol-2-yl-phenyl)-ethoxy]-pyridin-3-yl}-4-methyl-thiazol-2-yl)-propane-1,2-diol methanesulfonate, PF-06439015 methanesulfonate
Empirical Formula (Hill Notation): C22H23FN6O3S · CH3SO3H 分子量: 566.63 MDL编号: MFCD27978372 PubChem化学物质编号: 329823778 NACRES: NA.77
Empirical Formula (Hill Notation): C22H23FN6O3S · CH3SO3H 分子量: 566.63 MDL编号: MFCD27978372 PubChem化学物质编号: 329823778 NACRES: NA.77
¥1,591.58
PF-06442609,≥98% (HPLC)
PZ0258
别名:PF06442609;2-[(1S)-2-[4-氟-2-[(1R)-2,2,2-三氟-1-甲基乙基]苯氧基]-1-甲基乙基]-3,4-二氢-7-(4-甲基-1H-咪唑-1-基)-2H-吡啶并[1,2-a]吡嗪-1,6-二酮;2-[(2S)-1-{4-氟-2-[(2R)-1,1,1-三氟丙-2-基]苯氧基}丙-2-基]-7-(4-甲基-1H-咪唑-1-基)-3,4-二氢-2H-吡啶并[1,2-a]吡嗪-1,6-二酮;2-[(1S)-2-[4-Fluoro-2-[(1R)-2,2,2-trifluoro-1-methylethyl]phenoxy]-1-methylethyl]-3,4-dihydro-7-(4-methyl-1H-imidazol-1-yl)-2H-pyrido[1,2-a]pyrazine-1,6-dione;2-[(2S)-1-{4-Fluoro-2-[(2R)-1,1,1-trifluoropropan-2-yl]phenoxy}propan-2-yl]-7-(4-methyl-1H-imidazol-1-yl)-3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,6-dione, PF 06442609
Empirical Formula (Hill Notation): C24H24F4N4O3 CAS号: 1402002-76-9 分子量: 492.47 NACRES: NA.77
Empirical Formula (Hill Notation): C24H24F4N4O3 CAS号: 1402002-76-9 分子量: 492.47 NACRES: NA.77
¥1,591.58
PF06456384三盐酸盐,PF-06456384 trihydrochloride;≥98% (HPLC)
PZ0386
别名:3-氰基-4-[[3-[2-[2-(4-哌啶基)乙基]氨基]甲基]-4-吡啶基]-3′-(三氟甲基)[1,1′-联苯]-4-基]氧基]-N-1,2,4-噻二唑-5-基苯磺酰胺三盐酸盐;3-Cyano-4-[[3-[2-[[[2-(4-piperidinyl)ethyl]amino]methyl]-4-pyridinyl]-3′-(trifluoromethyl)[1,1′-biphenyl]-4-yl]oxy]-N-1,2,4-thiadiazol-5-yl-benzenesulfonamide trihydrochloride, Benzenesulfonamide, 3-cyano-4-[[3-[2-[[[2-(4-piperidinyl)ethyl]amino]methyl]-4-pyridinyl]-3′-(trifluoromethyl)[1,1′-biphenyl]-4-yl]oxy]-N-1,2,4-thiadiazol-5-yl-, hydrochloride (1:3)
Empirical Formula (Hill Notation): C35H32F3N7O3S2 · 3HCl CAS号: 1834610-75-1 分子量: 829.18
Empirical Formula (Hill Notation): C35H32F3N7O3S2 · 3HCl CAS号: 1834610-75-1 分子量: 829.18
¥1,856.00
PF-06459988,≥98% (HPLC)
PZ0296
别名:PF06459988;1-[(3R,4R)-3-[[[5-氯-2-[[1-甲基-1H-吡唑-4-基)氨基] -7H-吡咯并[2,3-d]嘧啶-4-基]氧基]甲基]-4-甲氧基-1-吡咯烷基]-2-丙烯-1-酮;1-[(3R,4R)-3-[[[5-Chloro-2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]methyl]-4-methoxy-1-pyrrolidinyl]-2-propen-1-one
Empirical Formula (Hill Notation): C19H22ClN7O3 CAS号: 1428774-45-1 分子量: 431.88 MDL编号: MFCD28987462 PubChem化学物质编号: 329823819 NACRES: NA.77
Empirical Formula (Hill Notation): C19H22ClN7O3 CAS号: 1428774-45-1 分子量: 431.88 MDL编号: MFCD28987462 PubChem化学物质编号: 329823819 NACRES: NA.77
¥1,591.58