PF-06281355 [PF-1355]，≥98% (HPLC)

图片 PF-06281355 [PF-1355]，≥98% (HPLC)
别名：PF06281355；6-(2,5-二甲氧基苯基)-3,4-二氢-4-氧代-2-硫代-1(2H)-嘧啶乙酰胺；6-(2,5-Dimethoxyphenyl)-3,4-dihydro-4-oxo-2-thioxo-1(2H)-pyrimidineacetamide, PF 6281355

Empirical Formula (Hill Notation): C14H15N3O4S CAS号: 1435467-38-1 分子量: 321.35 NACRES: NA.77
制造商品牌: 西格玛 Sigma-Aldrich
货号（SKU）: PZ0277
CAS号: 1435467-38-1
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¥1,591.58

说明

生化/生理作用

PF-06281355 (PF-1355) is an orally available, selective and potent mechanism based inhibitor of the myeloperoxidase (MPO) that reduces plasma MPO activity, vascular edema, neutrophil recruitment, and elevated circulating cytokines. PF-06281355 suppresses albuminuria and chronic renal dysfunction in model of anti-Glomerular Basement Membrane (GBM) disease.
 

其他说明

This compound was developed by Pfizer for Nitric Oxide & Cell Stress research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.
 

法律信息

Sold for research purposes under agreement from Pfizer Inc.
Pfizer is a registered trademark of Pfizer, Inc.
 
 

属性

质量水平

100

测定

≥98% (HPLC)

形式

powder

mfr. no.

Pfizer®

颜色

white to beige

溶解性

DMSO: 10 mg/mL, clear (warmed)

创始人

Pfizer

储存温度

room temp

 

安全信息

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H302

危险分类

Acute Tox. 4 Oral

储存分类代码

11 - Combustible Solids

WGK

WGK 3

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储存温度 Storage temp.常温阴凉避光
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