曲伐沙星甲磺酸盐，Trovafloxacin mesylate；>98% (HPLC)

图片 曲伐沙星甲磺酸盐，Trovafloxacin mesylate；>98% (HPLC)
别名：甲磺酸曲伐沙星；CP-99219-27；(1α,5α,6α)-7-(6-氨基-3-氮杂双环[3.1.0]己-3-基)-1-(2,4-二氟苯基)-6-氟-1,4-二氢-4-氧代-1,8-萘啶-3-羧酸甲磺酸酯；(1α,5α,6α)-7-(6-Amino-3-azabicyclo[3.1.0]hex-3-yl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid methanesulfonate, Trovafloxacin methanesulfonate

Empirical Formula (Hill Notation): C20H15F3N4O3 · CH3SO3H CAS号: 147059-75-4 分子量: 512.46 MDL编号: MFCD00913361 PubChem化学物质编号: 329823684 NACRES: NA.77
制造商品牌: 西格玛 Sigma-Aldrich
货号（SKU）: PZ0015
CAS号: 147059-75-4
MDL号: MFCD00913361
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¥1,593.84

说明

应用

Trovafloxacin mesylate has been used as a test compound in toxicity assay to assess its toxicity in 2D hepatocyte cultures.[1] It has also been used to manipulate the mechanism of apoptotic cell disassembly during apoptosis.[2]
 

生化/生理作用

Trovafloxacin mesylate acts as a pannexin1 (Panx1) inhibitor.[2]
Trovafloxacin mesylate is a broad spectrum antibiotic. Trovafloxacin mesylate blocks the activity of DNA gyrase and topoisomerase IV, enzymes essential in the repliction, transcription, and repair of bacterial DNA.
 

其他说明

This compound was developed by Pfizer for Immunology research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.
To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
 

法律信息

Sold for research purposes under agreement from Pfizer Inc.
Pfizer is a registered trademark of Pfizer, Inc.
 
 

属性

质量水平

100

测定

>98% (HPLC)

形式

powder

mfr. no.

Pfizer®

颜色

white to off-white

溶解性

DMSO: >10 mg/mL

创始人

Pfizer

储存温度

room temp

SMILES string

CS(O)(=O)=O.NC1C2CN(CC12)c3nc4N(C=C(C(O)=O)C(=O)c4cc3F)c5ccc(F)cc5F

InChI

1S/C20H15F3N4O3.CH4O3S/c21-8-1-2-15(13(22)3-8)27-7-12(20(29)30)17(28)9-4-14(23)19(25-18(9)27)26-5-10-11(6-26)16(10)24;1-5(2,3)4/h1-4,7,10-11,16H,5-6,24H2,(H,29,30);1H3,(H,2,3,4)/t10-,11+,16+;

InChI key

DYNZICQDCVYXFW-AHZSKCOESA-N

 

安全信息

象形图

CorrosionHealth hazard
GHS05,GHS08

警示用语：

Danger

危险声明

H314 - H361

危险分类

Repr. 2 - Skin Corr. 1B

储存分类代码

8A - Combustible, corrosive hazardous materials

WGK

WGK 3

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属性名称属性值
储存温度 Storage temp.常温阴凉避光
全球实时库存 Availability √美国St. Louis ≥ 20 | 欧洲Eur. ≥ 16 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 20
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