异柠檬酸脱氢酶1来源于人,Isocitrate Dehydrogenase 1 (NADP+) human [IDH1];recombinant, expressed in Sf9 cells, ≥90% (SDS-PAGE)

别名:异柠檬脱氢酶 (NADP);异柠檬酸脱氢酶胞质;Isocitrate Dehydrogenase Cytoplasmic

CAS号: 9028-48-2 EC 号: 1.1.1.42 (BRENDA, IUBMB) NACRES: NA.54
制造商品牌: 西格玛 Sigma-Aldrich
货号(SKU): I2411
CAS号: 9028-48-2
MDL号: MFCD00131420
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¥7,455.37

说明

一般描述

Human Isocitrate Dehydrogenase (IDH1), also known as oxalosuccinate decarboxylase, full length [amino acids 1-414 (end)] with C-terminal FLAG-tag, expressed in Sf9 cells via a baculovirus expression system.
 

应用

Human Isocitrate Dehydrogenase (IDH1) is useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. It may be useful as a biomarker for diagnosis and prognosis prediction of non-small cell lung cancer [1].
 

生化/生理作用

Human Isocitrate Dehydrogenase (IDH1), also known as oxalosuccinate decarboxylase, is a full length amino acid with a C-terminal FLAG-tag and is expressed in Sf9 cells via a baculovirus expression system. IDH1 expression has been correlated with poor survival of non-small cell lung cancer. IDH1 promotes tumor growth [1].
 

外形

Solution in 45 mM Tris-HCl, 124 mM NaCl, 2.4 mM KCl, 90 μg/ml FLAG peptide, 3 mM DTT, and 10% glycerol at pH 8.0.
 
 

属性

重组

expressed in Sf9 cells

质量水平

测定

≥90% (SDS-PAGE)

形式

buffered aqueous glycerol solution

分子量

47.6 kDa

浓度

≥0.30 mg/mL protein (Bradford)

NCBI登记号

相关疾病

cancer (lung)

运输

dry ice

储存温度

−70°C

 

安全信息

储存分类代码

12 - Non Combustible Liquids

WGK

WGK 1

商品规格
属性名称属性值
储存温度 Storage temp.-70°C超低温冷冻
全球实时库存 Availability √美国St. Louis ≥ 50 | 欧洲Eur. ≥ 12 | 東京Tokyo ≥ 20 | 香港与北京 ≥ 50