WAY208466二盐酸盐，WAY-208466 dihydrochloride；≥98% (HPLC)

图片 WAY208466二盐酸盐，WAY-208466 dihydrochloride；≥98% (HPLC)
别名：3-[(3-氟苯基)磺酰基]-N,N-二甲基-1H-吡咯并[2,3-b]吡啶-1-乙胺盐酸盐；WAY208466 dihydrochloride, WAY 208466 dihydrochloride, 3-[(3-Fluorophenyl)sulfonyl]-N,N-dimethyl-1H-pyrrolo[2,3-b]pyridine-1-ethanamine hydrochloride (1:2)

Empirical Formula (Hill Notation): C17H18FN3O2S · 2HCl CAS号: 1207064-61-6 分子量: 420.33 MDL编号: MFCD28384460 PubChem化学物质编号: 329823827 NACRES: NA.77
制造商品牌: 西格玛 Sigma-Aldrich
货号（SKU）: PZ0305
CAS号: 1207064-61-6
MDL号: MFCD28384460
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¥1,591.58

说明

生化/生理作用

WAY-208466 is a high affinity (Ki = 4.8 nM) 5-HT6 receptor agonist. In HeLa cells expressing cloned human 5-HT6, the compound induced cAMP production (EC50 = 7.3 nM; Emax = 100%). WAY-208466 increases cortical GABA levels and exhibits anxiolytic activity in rat studies.
 

其他说明

This compound was developed by Pfizer for Neuroscience research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.
To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
 

法律信息

Sold for research purposes under agreement from Pfizer Inc.
Pfizer is a registered trademark of Pfizer, Inc.
 
 

属性

质量水平

100

测定

≥98% (HPLC)

形式

powder

mfr. no.

Pfizer®

颜色

white to beige

溶解性

H2O: 5 mg/mL, clear (warmed)

创始人

Pfizer

储存温度

room temp

SMILES string

CN(C)CCN1C=C(S(C2=CC=CC(F)=C2)(=O)=O)C3=CC=CN=C31

InChI

1S/C17H18FN3O2S/c1-20(2)9-10-21-12-16(15-7-4-8-19-17(15)21)24(22,23)14-6-3-5-13(18)11-14/h3-8,11-12H,9-10H2,1-2H3

InChI key

SFSFIDVAEMDPIP-UHFFFAOYSA-N

 

安全信息

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H315 - H319 - H335

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

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储存温度 Storage temp.常温阴凉避光
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