UNC926，≥98% (HPLC)

图片 UNC926，≥98% (HPLC)
别名：(3-Bromophenyl)[4-(1-pyrrolidinyl)-1-piperidinyl]-methanone；(3-溴苯基)(4-(吡咯烷基-1-基)哌啶-1-基)甲酮

Empirical Formula (Hill Notation): C16H21BrN2O CAS号: 1184136-10-4 分子量: 337.25 MDL编号: MFCD23098916 PubChem化学物质编号: 329825550 NACRES: NA.77
制造商品牌: 西格玛 Sigma-Aldrich
货号（SKU）: SML0554
CAS号: 1184136-10-4
MDL号: MFCD23098916
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¥1,350.00

说明

生化/生理作用

UNC926 is a specific antagonist of the methyl-lysine binding protein L3MBTL1, a member of a protein family that reads the methylation state of histone lysine residues to direct gene expression. UNC926 dose dependently blocks the interaction of recombinant L3MBTL carrying three tandem MBT reader domains (L3MBTL3XMBT) and a methylated histone peptide H4K20me1 with an IC50 of 3.9 μM.
 
 

属性

检测方案

≥98% (HPLC)

形式

powder

颜色

white to light brown

溶解性

DMSO: 2 mg/mL, clear (warmed)

储存温度

2-8°C

SMILES string

Brc1cccc(c1)C(=O)N2CCC(CC2)N3CCCC3

InChI

1S/C16H21BrN2O/c17-14-5-3-4-13(12-14)16(20)19-10-6-15(7-11-19)18-8-1-2-9-18/h3-5,12,15H,1-2,6-11H2

InChI key

OWGLFIKZKQOYHZ-UHFFFAOYSA-N

 

安全信息

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 20 | 欧洲Eur. ≥ 16 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 20
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