信号通路, 信号转导, Cell Signaling

DS16570511 是一种细胞渗透性的线粒体钙单核转运蛋白 (mitochondrial calcium uniporter) 抑制剂，阻断了依赖于 MCU 或 MICU1 的 Ca2+ 流入增加。

别名：蛋白质二聚化的化学诱导剂；(2S,2′S)-1-[(2S)-1-oxo-2-(3,4,5-trimethoxyphenyl)butyl]-2-piperidinecarboxylic acid, 2,2′-[[2-[(dimethylamino)methyl]-1,3-propanediyl]bis[imino(2-oxo-2,1-ethanediyl)oxy-3,1-phenylene[(1R)-3-(3,4-dimethoxyphenyl)propylidene]]] ester

Empirical Formula (Hill Notation): C82H107N5O20 CAS号: 195514-80-8 分子量: 1482.75 MDL编号: MFCD28167729

别名：蛋白质二聚化的化学诱导剂；(2S,2′S)-1-[(2S)-1-oxo-2-(3,4,5-trimethoxyphenyl)butyl]-2-piperidinecarboxylic acid, 2,2′-[[2-[(dimethylamino)methyl]-1,3-propanediyl]bis[imino(2-oxo-2,1-ethanediyl)oxy-3,1-phenylene[(1R)-3-(3,4-dimethoxyphenyl)propylidene]]] ester

Empirical Formula (Hill Notation): C82H107N5O20 CAS号: 195514-80-8 分子量: 1482.75 MDL编号: MFCD28167729

别名: 2,6-吡啶二胺 三氟乙酸盐；N2-1H-吲哚-5-基-N6-甲基-3-硝基-2,6-吡啶二胺三氟乙酸盐；N2-（1H-吲唑-5-基）-N6-甲基-3-硝基吡啶-2,6-二胺三氟乙酸盐；2,6-Pyridinediamine trifluoroacetate salt, N2-(1H-Indazol-5-yl)-N6-methyl-3-nitropyridine-2,6-diamine trifluoroacetate salt, N2-1H-Indazol-5-yl-N6-methyl-3-nitro-2,6-pyridinediamine trifluoroacetate salt

Empirical Formula (Hill Notation): C13H12N6O2 · C2HF3O2 CAS号: 342639-96-7 分子量: 398.30 PubChem化学物质编号: 329825859 NACRES: NA.77

别名：3-(1,3-苯并二恶唑-5-基亚甲基)-2-氧-1-吡咯烷甲醛；3-(1,3-Benzodioxol-5-ylmethylene)-2-oxo-1-pyrrolidinecarboxaldehyde

Empirical Formula (Hill Notation): C13H11NO4 CAS号: 218924-25-5 分子量: 245.23 NACRES: NA.77

别名：N-[(2-羟基-1-萘基)亚甲基]-2-噻吩磺酰胺；N-[(2-Hydroxy-1-naphthalenyl)methylene]-2-thiophenesulfonamide

Empirical Formula (Hill Notation): C15H11NO3S2 CAS号: 307543-71-1 分子量: 317.38 MDL编号: MFCD02332975 PubChem化学物质编号: 329825404 NACRES: NA.77

别名：PARP-1和-2抑制剂；维利帕尼二盐酸盐；(R)-2-(2-甲基吡咯烷-2-基)-1H-苯并[d]咪唑-4-羧酰胺二盐酸盐；2-[(2R)-2-methyl-2-pyrrolidinyl]-1H-benzimidazole-7-carboxamide, dihydrochloride

CAS：912445-05-7；分子式：C13H18Cl2N4O；分子量：317.21

别名：(z)-N-(2-羟基-3-(哌啶-1-基)丙氧基)烟酰胺双盐酸盐；N-(2-hydroxy-3-(piperidin-1-yl)propoxy)nicotinimidamide dihydrochloride

CAS：66611-37-8；分子式：C14H24Cl2N4O2；分子量：351.27

别名：3,5,7,8-四氢-2-[4-（三氟甲基）苯基]-4H-噻喃并[4,3-d]嘧啶-4-酮；3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one

Empirical Formula (Hill Notation): C14H11F3N2OS CAS号: 284028-89-3 分子量: 312.31 MDL编号: MFCD16879017 PubChem化学物质编号: 329830802 NACRES: NA.77

别名：(S)-2-(3-(吡啶-2-基甲氧基)吡咯烷-1-基)-5-(三氟甲基)苯甲酸；(S)-2-(3-(Pyridin-2-ylmethoxy)pyrrolidin-1-yl)-5-(trifluoromethyl)benzoic acid

Empirical Formula (Hill Notation): C18H17F3N2O3 CAS号: 1515856-92-4 分子量: 366.33

别名：trans-ISRIB；反式-N,N′-1,4-环己烷二基双 \ [2-（4-氯苯氧基）-乙酰胺；反式-N,N′-（环己烷-1,4-二基）双（2-（4-氯苯氧基）乙酰胺；整合应激反应抑制剂；Integrated Stress Response inhibitor, trans-N,N′-(Cyclohexane-1,4-diyl)bis(2-(4-chlorophenoxy)acetamide, trans-N,N′-1,4-Cyclohexanediylbis[2-(4-chlorophenoxy)-acetamide

Empirical Formula (Hill Notation): C22H24Cl2N2O4 CAS号: 1597403-47-8 分子量: 451.34 PubChem化学物质编号: 329825607 NACRES: NA.77

别名：GW1929水合物；N-(2-Benzoylphenyl)-O-[2-(methyl-2-pyridinylamino)ethyl]-L-tyrosine hydrate；N-（2-苄基苯基）-O- [2-（甲基-2-吡啶基氨基）乙基] -L-酪氨酸水合物

Empirical Formula (Hill Notation): C30H29N3O4 · xH2O 分子量: 495.57 (anhydrous basis) PubChem化学物质编号: 24278789 NACRES: NA.77