信号通路, 信号转导, Cell Signaling

20,000多种特异性抑制剂、激动剂作用于表观遗传学、PI3K/Akt/mTOR、凋亡、MAPK、Wnt等20多个信号通路的375个靶点蛋白,覆盖癌症、神经科学、免疫学等热门疾病研究领域。BSZH北实纵横科学公司的50多种活性化合物库,包含10,000多种具有生物活性的小分子化合物,可用于高通量筛选 (HTS)和高内涵筛选 (HCS),是进行新药筛选和新适应症发现等研究的专业工具。

浏览为
排序由
显示 每页

A-395N,≥98% (HPLC)

SML1879
别名:(3S,4R)-{1-苄基-N,N-二甲基-4-(4-(甲基磺酰基)哌嗪-1-基)苯基)吡咯烷-3-胺;(3S,4R)-1-苄基-4-[4-(4-甲磺酰基哌嗪-1-基)苯基]-吡咯烷-3-基}-二甲基胺;(3S,4R)-{1-Benzyl-4-[4-(4-methanesulfonyl-piperazin-1-yl)-phenyl]-pyrrolidin-3-yl}-dimethyl-amine, (3S,4R)-1-Benzyl-N,N-dimethyl-4-(4-(4-(methylsulfonyl)piperazin-1-yl)phenyl)pyrrolidin-3-amine

Empirical Formula (Hill Notation): C24H34N4O2S 分子量: 442.62
¥1,591.58

A-485,≥98% (HPLC)

SML2192
别名:N-(4-氟苄基)-2-((R)-5-(3-甲基脲基)-2',4'-二氧代-2,3-二氢螺[茚-1,5'-恶唑烷]-3'-基)-N-((S)-1,1,1-三氟丙-2-基)乙酰胺;N-(4-fluorobenzyl)-2-((R)-5-(3-methylureido)-2′,4′-dioxo-2,3-dihydrospiro[indene-1,5′-ozazolidine]-3′-7 yl)-N-((S)-1,1,1-trifluoropropan-2-yl)acetamide, Spiro[1H-indene-1,5′-oxazolidine]-3′-acetamide, N-[(4-fluorophenyl)methyl]-2,3-dihydro-5-[[(methylamino)carbonyl]amino]-2′,4′-dioxo-N-[(1S)-2,2,2-trifluoro-1-methylethyl]-, (1R)-

Empirical Formula (Hill Notation): C25H24F4N4O5 CAS号: 1889279-16-6 分子量: 536.48 MDL编号: MFCD31619258
¥2,049.13

BAY-364,≥98% (HPLC)

SML1783
别名:BAY-299N;6-(3-羟丙基)-2-(1-甲基-2-氧代-2,3-二氢-1H-苯并咪唑-5-基)-1H-苯并去]异喹啉-1,3(2H)-二酮;6-(3-Hydroxypropyl)-2-(1-methyl-2-oxo-2,3-dihydro-1H-benzimidazol-5-yl)-1H-benzo[de]isoquinoline-1,3(2H)-dione

Empirical Formula (Hill Notation): C23H19N3O4 分子量: 401.41 NACRES: NA.77
¥2,146.68

BAY-588,≥98% (HPLC)

SML1780
别名:N4-[1-[[4-(1,1-二甲基乙基)苯基]甲基]-5-甲基-3-(三氟甲基)-1H-吡唑-4-基]-7-氟-2,4-喹啉二甲酰胺;N4-[1-[[4-(1,1-Dimethylethyl)phenyl]methyl]-5-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]-7-fluoro-2,4-quinolinedicarboxamide

Empirical Formula (Hill Notation): C27H25F4N5O2 CAS号: 1799759-24-2 分子量: 527.51 PubChem化学物质编号: 329826061
¥2,976.73

BAY-598,≥98% (HPLC)

SML1603
别名:(S)-N-[1-{N'-氰基-N-[3-(二氟甲氧基)苯基]氨基甲酰氨基}-3-(3,4-二氯苯基)-4,5-二氢-1H-吡唑-4- 基]-N-乙基-2-羟基乙酰胺;(S)-N-[1-{N′-Cyano-N-[3-(difluoromethoxy)phenyl]carbamimidoyl}-3-(3,4-dichlorophenyl)-4,5-dihydro-1H-pyrazol-4-yl]-N-ethyl-2-hydroxyacetamide

Empirical Formula (Hill Notation): C22H20Cl2F2N6O3 分子量: 525.34 PubChem化学物质编号: 329825489
¥3,435.20

BAY-6035,≥98% (HPLC)

SML2325
别名:BAY6035, BAY 6035, (2S)-1-(3-Azabicyclo[3.1.0]hexane-3-carbonyl)-N-(2-cyclopropylethyl)-2-methyl-4-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepine-7-carboxamide;(2S)-1-(3-氮杂双环[3.1.0]己烷-3-羰基)-N-(2-环丙基乙基)-2-甲基-4-氧代-2,3,4,5-四氢-1H- 苯并[b][1,4]二氮杂-7-甲酰胺

Empirical Formula (Hill Notation): C22H28N4O3 分子量: 396.48 NACRES: NA.77
¥1,526.04

BAY-677,≥98% (HPLC)

SML1564
别名:5-{(4S)-5-Acetyl-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydropyrimidin-4-yl}pyridine-2-carbonitrile, 2-Pyridinecarbonitrile, 5-[(4S)-5-acetyl-1,2,3,4-tetrahydro-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-4-pyrimidinyl]-, (S)-BAY-678

Empirical Formula (Hill Notation): C20H15F3N4O2 分子量: 400.35 PubChem化学物质编号: 329825967 NACRES: NA.77
¥2,367.30

BAY-678,≥98% (HPLC)

SML1563
别名:5-{(4R)-5-Acetyl-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydropyrimidin-4-yl}pyridine-2-carbonitrile, 2-Pyridinecarbonitrile, 5-[(4R)-5-acetyl-1,2,3,4-tetrahydro-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-4-pyrimidinyl]-

Empirical Formula (Hill Notation): C20H15F3N4O2 CAS号: 675103-36-3 分子量: 400.35 MDL编号: MFCD29924806 PubChem化学物质编号: 329825966 NACRES: NA.77
¥1,591.58

BAY-876,≥98% (HPLC)

SML1774
别名:N4- [1-[(4-氰基苯基)甲基] -5-甲基-3-(三氟甲基)-1H-吡唑-4-基] -7-氟-2,4-喹啉二甲酰胺;N4-[1-[(4-Cyanophenyl)methyl]-5-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]-7-fluoro-2,4-quinolinedicarboxamide

Empirical Formula (Hill Notation): C24H16F4N6O2 CAS号: 1799753-84-6 分子量: 496.42 PubChem化学物质编号: 329826059
¥2,576.73

BAZ2-ICR,≥98% (HPLC)

SML1276
别名:4-{4-(1-甲基-1H-吡唑-4-基)-1-[2-(1-甲基-1H-吡唑-4-基)-乙基]-1H-咪唑-5-基}- 苄腈;4-{4-(1-Methyl-1H-pyrazol-4-yl)-1-[2-(1-methyl-1H-pyrazol-4-yl)-ethyl]-1H-imidazol-5-yl}-benzonitrile

Empirical Formula (Hill Notation): C20H19N7 分子量: 357.41 MDL编号: MFCD28166490 PubChem化学物质编号: 329825762 NACRES: NA.77
¥2,285.40

BI-9564,≥97% (HPLC)

SML1655
别名:4-(4-二甲氨基甲基-2,5-二甲氧基苯基)-2-甲基-2H-[2,7]萘啶-1-酮;4-[4-[二甲基氨基甲基]-2,5-二甲氧基苯基]-2-甲基-2,7-萘啶-1-酮;4-(4-Dimethylaminomethyl-2,5-dimethoxy-phenyl)-2-methyl-2H-[2,7]naphthyridin-1-one, 4-[4-[(Dimethylamino)methyl]-2,5-dimethoxyphenyl]-2-methyl-2,7-naphthyridin-1-one, GTPL8950

Empirical Formula (Hill Notation): C20H23N3O3 CAS号: 1883429-22-8 分子量: 353.41 PubChem化学物质编号: 329825994 NACRES: NA.77
¥1,785.40

BI01383298,≥98% (HPLC)

SML2214
别名:BI 01383298;BI-01383298;1-(3,5-二氯苯基磺酰基)-N-(4-氟苄基)哌啶-4-甲酰胺;1-(3,5-Dichlorophenylsulfonyl)-N-(4-fluorobenzyl)piperidine-4-carboxamide

Empirical Formula (Hill Notation): C19H19Cl2FN2O3S CAS号: 2227549-00-8 分子量: 445.34
¥1,020.39