信号通路, 信号转导, Cell Signaling
20,000多种特异性抑制剂、激动剂作用于表观遗传学、PI3K/Akt/mTOR、凋亡、MAPK、Wnt等20多个信号通路的375个靶点蛋白,覆盖癌症、神经科学、免疫学等热门疾病研究领域。BSZH北实纵横科学公司的50多种活性化合物库,包含10,000多种具有生物活性的小分子化合物,可用于高通量筛选 (HTS)和高内涵筛选 (HCS),是进行新药筛选和新适应症发现等研究的专业工具。
浏览为
排序由
显示 每页
PF06305591二水合物,PF-06305591 dihydrate;≥98% (HPLC)
PZ0297
别名:αR, βS-β-氨基-6-(1,1-二甲基乙基)-α-甲基-1H-苯并咪唑-2-丙酰胺二水合物;(αR,βS)-β-Amino-6-(1,1-dimethylethyl)-α-methyl-1H-benzimidazole-2-propanamide dihydrate
Empirical Formula (Hill Notation): C15H22N4O · 2H2O CAS号: 1449473-97-5 (anhydrous) 分子量: 310.39 PubChem化学物质编号: 329823820 NACRES: NA.77
Empirical Formula (Hill Notation): C15H22N4O · 2H2O CAS号: 1449473-97-5 (anhydrous) 分子量: 310.39 PubChem化学物质编号: 329823820 NACRES: NA.77
¥1,591.58
PF06412154盐酸盐,PF-06412154 hydrochloride;≥98% (HPLC)
PZ0333
别名:N-[4-[(1R)-1-[(3-甲基-2-喹啉基)氨基]丁基]苯甲酰基]-β-丙氨酸盐酸盐;N-[4-[(1R)-1-[(3-Methyl-2-quinolinyl)amino]butyl]benzoyl]-β-alanine hydrochloride
Empirical Formula (Hill Notation): C24H27N3O3 · HCl CAS号: 1421349-19-0 分子量: 441.95 PubChem化学物质编号: 329823844
Empirical Formula (Hill Notation): C24H27N3O3 · HCl CAS号: 1421349-19-0 分子量: 441.95 PubChem化学物质编号: 329823844
¥1,591.58
PF-06412562,≥98% (HPLC)
PZ0357
别名:PF06412562;4-[4-(4,6-二甲基-5-嘧啶基)-3-甲基苯氧基]-1H-吡唑并[4,3-c]吡啶;4-[4-(4,6-二甲基嘧啶-5-基)-3-甲基苯氧基]-1H-吡唑并[4,3-c]吡啶;4-[4-(4,6-Dimethyl-5-pyrimidinyl)-3-methylphenoxy]-1H-pyrazolo[4,3-c]pyridine, PF 06412562, PF06412562, 4-[4-(4,6-Dimethylpyrimidin-5-yl)-3-methylphenoxy]-1H-pyrazolo[4,3-c]pyridine
Empirical Formula (Hill Notation): C19H17N5O CAS号: 1609258-91-4 分子量: 331.37
Empirical Formula (Hill Notation): C19H17N5O CAS号: 1609258-91-4 分子量: 331.37
¥1,591.58
PF-06422913,≥98% (HPLC)
PZ0334
别名:1-甲基-6-(2-吡啶甲氧基)-3-[4-三氟甲基-3-吡啶基]-1H-吡唑并[3,4-b]哌嗪;1-Methyl-6-(2-pyridinylmethoxy)-3-[4-(trifluoromethyl)-3-pyridinyl]-1H-pyrazolo[3,4-b]prazine, PF06422913;PF06422913
Empirical Formula (Hill Notation): C18H13F3N6O CAS号: 1539296-46-2 分子量: 386.33 PubChem化学物质编号: 329823845
Empirical Formula (Hill Notation): C18H13F3N6O CAS号: 1539296-46-2 分子量: 386.33 PubChem化学物质编号: 329823845
¥1,591.58
PF06439015甲磺酸盐,PF-06439015 methanesulfonate salt;≥98% (HPLC)
PZ0221
别名:PF-06439015 mesylate;2R-(5-{6-氨基-5-[1R-(5-氟-2-[1,2,3]三唑-2-基苯基)乙氧基]-吡啶-3-基}-4-甲基噻唑-2-基)-丙烷-1,2-二醇甲磺酸酯;2R-(5-{6-Amino-5-[1R-(5-fluoro-2-[1,2,3]triazol-2-yl-phenyl)-ethoxy]-pyridin-3-yl}-4-methyl-thiazol-2-yl)-propane-1,2-diol methanesulfonate, PF-06439015 methanesulfonate
Empirical Formula (Hill Notation): C22H23FN6O3S · CH3SO3H 分子量: 566.63 MDL编号: MFCD27978372 PubChem化学物质编号: 329823778 NACRES: NA.77
Empirical Formula (Hill Notation): C22H23FN6O3S · CH3SO3H 分子量: 566.63 MDL编号: MFCD27978372 PubChem化学物质编号: 329823778 NACRES: NA.77
¥1,591.58
PF-06442609,≥98% (HPLC)
PZ0258
别名:PF06442609;2-[(1S)-2-[4-氟-2-[(1R)-2,2,2-三氟-1-甲基乙基]苯氧基]-1-甲基乙基]-3,4-二氢-7-(4-甲基-1H-咪唑-1-基)-2H-吡啶并[1,2-a]吡嗪-1,6-二酮;2-[(2S)-1-{4-氟-2-[(2R)-1,1,1-三氟丙-2-基]苯氧基}丙-2-基]-7-(4-甲基-1H-咪唑-1-基)-3,4-二氢-2H-吡啶并[1,2-a]吡嗪-1,6-二酮;2-[(1S)-2-[4-Fluoro-2-[(1R)-2,2,2-trifluoro-1-methylethyl]phenoxy]-1-methylethyl]-3,4-dihydro-7-(4-methyl-1H-imidazol-1-yl)-2H-pyrido[1,2-a]pyrazine-1,6-dione;2-[(2S)-1-{4-Fluoro-2-[(2R)-1,1,1-trifluoropropan-2-yl]phenoxy}propan-2-yl]-7-(4-methyl-1H-imidazol-1-yl)-3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,6-dione, PF 06442609
Empirical Formula (Hill Notation): C24H24F4N4O3 CAS号: 1402002-76-9 分子量: 492.47 NACRES: NA.77
Empirical Formula (Hill Notation): C24H24F4N4O3 CAS号: 1402002-76-9 分子量: 492.47 NACRES: NA.77
¥1,591.58
PF06456384三盐酸盐,PF-06456384 trihydrochloride;≥98% (HPLC)
PZ0386
别名:3-氰基-4-[[3-[2-[2-(4-哌啶基)乙基]氨基]甲基]-4-吡啶基]-3′-(三氟甲基)[1,1′-联苯]-4-基]氧基]-N-1,2,4-噻二唑-5-基苯磺酰胺三盐酸盐;3-Cyano-4-[[3-[2-[[[2-(4-piperidinyl)ethyl]amino]methyl]-4-pyridinyl]-3′-(trifluoromethyl)[1,1′-biphenyl]-4-yl]oxy]-N-1,2,4-thiadiazol-5-yl-benzenesulfonamide trihydrochloride, Benzenesulfonamide, 3-cyano-4-[[3-[2-[[[2-(4-piperidinyl)ethyl]amino]methyl]-4-pyridinyl]-3′-(trifluoromethyl)[1,1′-biphenyl]-4-yl]oxy]-N-1,2,4-thiadiazol-5-yl-, hydrochloride (1:3)
Empirical Formula (Hill Notation): C35H32F3N7O3S2 · 3HCl CAS号: 1834610-75-1 分子量: 829.18
Empirical Formula (Hill Notation): C35H32F3N7O3S2 · 3HCl CAS号: 1834610-75-1 分子量: 829.18
¥1,856.00
PF-06459988,≥98% (HPLC)
PZ0296
别名:PF06459988;1-[(3R,4R)-3-[[[5-氯-2-[[1-甲基-1H-吡唑-4-基)氨基] -7H-吡咯并[2,3-d]嘧啶-4-基]氧基]甲基]-4-甲氧基-1-吡咯烷基]-2-丙烯-1-酮;1-[(3R,4R)-3-[[[5-Chloro-2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]methyl]-4-methoxy-1-pyrrolidinyl]-2-propen-1-one
Empirical Formula (Hill Notation): C19H22ClN7O3 CAS号: 1428774-45-1 分子量: 431.88 MDL编号: MFCD28987462 PubChem化学物质编号: 329823819 NACRES: NA.77
Empirical Formula (Hill Notation): C19H22ClN7O3 CAS号: 1428774-45-1 分子量: 431.88 MDL编号: MFCD28987462 PubChem化学物质编号: 329823819 NACRES: NA.77
¥1,591.58
PF-06462894,≥98% (HPLC)
PZ0231
别名:PF06462894;6,2-二甲基丙基-2-吡啶-2-甲氧基吡啶-6,7-二氢-9H-嘧啶并[2,1-c][1,4]恶嗪-4-酮;6(R)-(2,2-Dimethyl-propyl)-2-(pyridin-2-ylmethoxy)-6,7-dihydro-9H-pyrimido[2,1-c][1,4]oxazin-4-one
Empirical Formula (Hill Notation): C18H23N3O3 分子量: 329.39 MDL编号: MFCD28137683 PubChem化学物质编号: 329823782 NACRES: NA.77
Empirical Formula (Hill Notation): C18H23N3O3 分子量: 329.39 MDL编号: MFCD28137683 PubChem化学物质编号: 329823782 NACRES: NA.77
¥1,864.05
PF-06465469,≥97% (HPLC)
PZ0209
别名:PF06465469;3-[4-氨基-1-(3R)-1-(1-氧代-2-丙烯-1-基)-3-哌啶基]-1H-吡唑并[3,4-d]嘧啶-3-基]-N-[3-甲基-4-(1-甲基乙基)苯基]苯甲酰胺;3-[4-Amino-1-[(3R)-1-(1-oxo-2-propen-1-yl)-3-piperidinyl]-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-N-[3-methyl-4-(1-methylethyl)phenyl]-benzamide
Empirical Formula (Hill Notation): C30H33N7O2 CAS号: 1407966-77-1 分子量: 523.63 NACRES: NA.77
Empirical Formula (Hill Notation): C30H33N7O2 CAS号: 1407966-77-1 分子量: 523.63 NACRES: NA.77
¥1,530.00
PF-06649283,≥98% (HPLC)
PZ0261
别名:PF06649283;(4R,4aR,6R,8aS)-8a-(2,4-Difluorophenyl)-4,4a,5,6,8,8a-hexahydro-4-methyl-6-(3-methyl-5-isoxazolyl)-pyrano[3,4-d][1,3]thiazin-2-amine, (4R,4aR,6R,8aS)-8a-(2,4-Difluoro-phenyl)-4-methyl-6-(3-methyl-isoxazol-5-yl)-4,4a,5,6,8,8a-hexahydro-7-oxa-3-thia-1-aza-naphthalen-2-ylamine
Empirical Formula (Hill Notation): C18H19F2N3O2S CAS号: 1621585-17-8 分子量: 379.42 MDL编号: MFCD28580118 PubChem化学物质编号: 329823797 NACRES: NA.77
Empirical Formula (Hill Notation): C18H19F2N3O2S CAS号: 1621585-17-8 分子量: 379.42 MDL编号: MFCD28580118 PubChem化学物质编号: 329823797 NACRES: NA.77
¥1,591.58
PF-06651385,≥98% (HPLC)
PZ0381
别名:PF06651385;4-(3-氯-4-三氟甲氧基)苄氧基)-N-(1,2,4-噻二唑-5-基)苯磺酰胺;4-(3-Chloro-4-(trifluoromethoxy)benzyloxy)-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide, PF 06651385
Empirical Formula (Hill Notation): C16H11ClF3N3O4S2 分子量: 465.85 NACRES: NA.77
Empirical Formula (Hill Notation): C16H11ClF3N3O4S2 分子量: 465.85 NACRES: NA.77
¥1,339.59