SB 699551 dihydrochloride，≥98% (HPLC)

图片 SB 699551 dihydrochloride，≥98% (HPLC)
别名：SB699551二盐酸盐；N-2-(二甲氨基)乙基-N-4'-(2-苯乙基)氨基甲基1,1'-联苯-4-基甲基-环戊烷丙酰胺二盐酸盐；N-2-(Dimethylamino)ethyl-N-4′-(2-phenylethyl)aminomethyl1,1′-biphenyl-4-ylmethyl-cyclopentanepropanamide dihydrochloride

Empirical Formula (Hill Notation): C34H45N3O · 2HCl CAS号: 864741-95-7 分子量: 584.66 NACRES: NA.77
制造商品牌: 西格玛 Sigma-Aldrich
货号（SKU）: SML0853
CAS号: 864741-95-7
MDL号: MFCD11112202
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¥1,364.05

说明

应用

SB 699551 dihydrochloride has been used to identify the antagonism of 5-HT2AR in cell culture-derived hepatitis C virus (HCVcc).[1]
 

生化/生理作用

SB 699551 dihydrochloride is also known as (3-cyclopentyl-N-[2-(dimethylamino)ethyl]-N-[(4′-{[(2-phenylethyl)amino]methyl}-4-biphenylyl)methyl]propanamide dihydrochloride).[2] It is considered as a useful tool to explain the physiological roles of the 5-ht5A receptor.[2]
SB-699551 is a 5-HT5A receptor antagonist, (pKi = 8.3) with 100-fold selectivity over other 5-HT receptor populations. SB-699551 completely blocks 5-HT-induced [35S]GTPγS membrane binding in cells expressing recombinant guinea pig 5-HT-5A.
 
 

属性

质量水平

100

检测方案

≥98% (HPLC)

形式

powder

颜色

white to beige

溶解性

H2O: 1 mg/mL, clear (warmed)

储存温度

2-8°C

InChI

1S/C34H45N3O.2ClH/c1-36(2)24-25-37(34(38)21-16-28-10-6-7-11-28)27-31-14-19-33(20-15-31)32-17-12-30(13-18-32)26-35-23-22-29-8-4-3-5-9-29;;/h3-5,8-9,12-15,17-20,28,35H,6-7,10-11,16,21-27H2,1-2H3;2*1H

InChI key

QJMKBIHLMPTYTI-UHFFFAOYSA-N

 

安全信息

储存分类代码

11 - Combustible Solids

WGK

WGK 3

商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 20 | 欧洲Eur. ≥ 16 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 20
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