PF-4778574，≥98% (HPLC)

图片 PF-4778574，≥98% (HPLC)
别名：N-{(3R,4S)-3-4-(5-氰基-2-噻吩基)苯基]四氢-2H-吡喃-4-基]-2-丙烷磺酰胺；N-(3R,4S)-3-4-(5-氰基-2-噻吩基)苯基]四氢-2H-吡喃-4-基}丙烷-2-磺酰胺；N-{(3R,4S)-3-4-(5-Cyano-2-thienyl)phenyltetrahydro-2H-pyran-4-yl}propane-2-sulfonamide, N-(3R,4S)-3-4-(5-Cyano-2-thienyl)phenyltetrahydro-2H-pyran-4-yl-2-propanesulfonamide

Empirical Formula (Hill Notation): C19H22N2O3S2 CAS号: 1219633-99-4 分子量: 390.52 NACRES: NA.77
制造商品牌: 西格玛 Sigma-Aldrich
货号（SKU）: PZ0211
CAS号: 1219633-99-4
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¥1,504.01

说明

应用

PF-4778574 may be used as a potentiator of the α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor (AMPAR) in rat cortical neurons.[1]
 

生化/生理作用

PF-4778574 is a potent AMPA receptor positive allosteric modulator (PAM) that has been shown to enhance cognition in animal models.
 

特点和优势

This compound is featured on the Glutamate Receptors (Ion Channel Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
 

其他说明

This compound was developed by Pfizer for Neuroscience research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.
To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
 

法律信息

Sold for research purposes under agreement from Pfizer Inc.
Pfizer is a registered trademark of Pfizer, Inc.
 
 

属性

质量水平

100

检测方案

≥98% (HPLC)

形式

powder

manufacturer/tradename

Pfizer®

颜色

white to beige

溶解性

DMSO: 20 mg/mL, clear

创始人

Pfizer

储存温度

room temp

InChI

1S/C19H22N2O3S2/c1-13(2)26(22,23)21-18-9-10-24-12-17(18)14-3-5-15(6-4-14)19-8-7-16(11-20)25-19/h3-8,13,17-18,21H,9-10,12H2,1-2H3/t17-,18+/m1/s1

InChI key

FFAGHPLLBXWCSF-MSOLQXFVSA-N

 

安全信息

储存分类代码

11 - Combustible Solids

WGK

WGK 3

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