PF-04628935，≥98% (HPLC)

图片 PF-04628935，≥98% (HPLC)
别名：PF-4628935；PF04628935；1-[2-[2-氯-4-（2H-1,2,3-三唑-2-基）苯基]甲基]-2,7-二氮杂螺[3.5]非-7-基]-2-（2-甲基咪唑并[2,1-b]噻唑-6-基）乙酮；1-[2-[[2-Chloro-4-(2H-1,2,3-triazol-2-yl)phenyl]methyl]-2,7-diazaspiro[3.5]non-7-yl]-2-(2-methylimidazo[2,1-b]thiazol-6-yl)-ethanone

Empirical Formula (Hill Notation): C24H26ClN7OS CAS号: 1383719-97-8 分子量: 496.03
制造商品牌: 西格玛 Sigma-Aldrich
货号（SKU）: PZ0228
CAS号: 1383719-97-8
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¥1,591.58

说明

生化/生理作用

PF-04628935 is a potent antagonist/inverse agonist of the ghrelin receptor, growth hormone secretagogue receptor 1a (GHS-R1a) with an IC50 of 4.6 nM. Ghrelin and GSHR are involved in regulation of food intake and long-term energy homeostasis; GSHR ligands are of interest for obesity and other metabolic disorders. PF-04628935 is orally bioavailable and brain penetrant.
 

其他说明

This compound was developed by Pfizer for Cytokines & Growth Factors research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.
To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
 

法律信息

Sold for research purposes under agreement from Pfizer Inc.
Pfizer is a registered trademark of Pfizer, Inc.
 
 

属性

质量水平

100

测定

≥98% (HPLC)

形式

powder

mfr. no.

Pfizer®

颜色

white to beige

溶解性

DMSO: 10 mg/mL, clear

创始人

Pfizer

储存温度

room temp

 

安全信息

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

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属性名称属性值
储存温度 Storage temp.常温阴凉避光
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