PF04363467盐酸盐，PF-04363467 hydrochloride；≥98% (HPLC)

图片 PF04363467盐酸盐，PF-04363467 hydrochloride；≥98% (HPLC)
别名：4-(4-乙基-2-吗啉基)-2-甲基苯基]-4-(1-甲基乙基)苯磺酰胺盐酸盐；N-[4-[(2S)-4-乙基-2-吗啉基]-2-甲基苯基]-4-（1-甲基乙基）苯磺酰胺盐酸盐；N-[4-[(2S)-4-Ethyl-2-morpholinyl]-2-methylphenyl]-4-(1-methylethyl)-benzenesulfonamide hydrochloride, (S)-N-[4-(4-Ethyl-2-morpholinyl)-2-methylphenyl]-4-(1-methylethyl)benzenesulfonamide hydrochloride, PF-4363467 hydrochloride

Empirical Formula (Hill Notation): C22H30N2O3S · HCl CAS号: 2040055-81-8 (free base) 分子量: 439.01 NACRES: NA.77
制造商品牌: 西格玛 Sigma-Aldrich
货号（SKU）: PZ0354
CAS号: 2040055-81-8
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¥1,591.58

说明

生化/生理作用

PF-4363467 hydrochloride is a Dopamine D3/D2 receptor antagonist. PF-4363467 has 100-fold selectivity for D3 with a Ki value of 3.1 nM for D3R compared to a Ki value of 692 nM for D2R and high selectivity for D3R compared to other biogenic amine receptors. PF-4363467 attenuated opioid drug-seeking behavior in a rat model of addiction without causing the extrapyramidal symptoms often associated with D2R antagonism.
 

法律信息

Sold for research purposes under agreement from Pfizer Inc.
Pfizer is a registered trademark of Pfizer, Inc.
 
 

属性

质量水平

100

测定

≥98% (HPLC)

形式

powder

mfr. no.

Pfizer®

颜色

white to beige

溶解性

H2O: 3 mg/mL, clear (warmed)

创始人

Pfizer

储存温度

room temp

SMILES string

[H]Cl.CC1=CC([C@H]2CN(CC)CCO2)=CC=C1NS(C3=CC=C(C(C)C)C=C3)(=O)=O

 

安全信息

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

商品规格
属性名称属性值
储存温度 Storage temp.常温阴凉避光
全球实时库存 Availability √美国St. Louis ≥ 20 | 欧洲Eur. ≥ 16 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 20
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