PF-01247324,≥98% (HPLC)

别名:PF01247324;6-氨基-5-(2,3,5-三氯苯基)吡啶-2-羧酸甲酰胺;6-氨基-5-(2,3,5-三氯苯基)吡啶-2-甲酰胺;N-甲基-6-氨基-5-(2,3,5-三氯苯基)吡啶-2-甲酰胺;N-Methyl-6-amino-5-(2,3,5-trichlorophenyl)pyridine-2-carboxamide, 6-Amino-N-methyl-5-(2,3,5-trichlorophenyl)-2-Pyridinecarboxamide, 6-Amino-5-(2,3,5-trichlorophenyl)pyridine-2-carboxylic acid methylamide, PF-1247324, PF 01247324

Empirical Formula (Hill Notation): C13H10Cl3N3O CAS号: 875051-72-2 分子量: 330.60 NACRES: NA.77
制造商品牌: 西格玛 Sigma-Aldrich
货号(SKU): PZ0274
CAS号: 875051-72-2
MDL号: MFCD28156579
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¥1,091.58

说明

生化/生理作用

In humans, PF-01247324 [6-amino-5-(2, 3, 5-trichloro-phenyl)-pyridine-2-carboxylic acid methylamide] prevents native tetrodotoxin-resistant (TTX-R) currents in dorsal root ganglion (DRG) neurons.[1]
PF-01247324 is an orally bioavailable, selective and potent NaV1.8 channel blocker that inhibits that exhibits analgesic efficacy in rodent behavioral models of pain.
 

其他说明

This compound was developed by Pfizer for Ion Channel research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.
To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
 

法律信息

Sold for research purposes under agreement from Pfizer Inc.
Pfizer is a registered trademark of Pfizer, Inc.
 
 

属性

质量水平

100

测定

≥98% (HPLC)

形式

powder

mfr. no.

Pfizer®

颜色

white to beige

溶解性

DMSO: 20 mg/mL, clear

创始人

Pfizer

储存温度

room temp

 

安全信息

象形图

Skull and crossbones

警示用语:

Danger

危险分类

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

商品规格
属性名称属性值
储存温度 Storage temp.常温阴凉避光
全球实时库存 Availability √美国St. Louis ≥ 20 | 欧洲Eur. ≥ 16 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 20