OICR-9429，≥98% (HPLC)

图片 OICR-9429，≥98% (HPLC)
别名：6-氧代-4-三氟甲基-1,6-二氢-吡啶-3-羧酸[4-(4-甲基-哌嗪-1-基)-3'-吗啉-4-基甲基-联苯-3-基] -酰胺；6-Oxo-4-trifluoromethyl-1,6-dihydro-pyridine-3-carboxylic acid [4-(4-methyl-piperazin-1-yl)-3′-morpholin-4-ylmethyl-biphenyl-3-yl]-amide

Empirical Formula (Hill Notation): C29H32F3N5O3 CAS号: 1801787-56-3 分子量: 555.59 MDL编号: MFCD18364451 PubChem化学物质编号: 329825720 NACRES: NA.77
制造商品牌: 西格玛 Sigma-Aldrich
货号（SKU）: SML1209
CAS号: 1801787-56-3
MDL号: MFCD18364451
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¥1,921.00

说明

生化/生理作用

OICR-9429 is a cell penetrant, potent and selective antagonist of the interaction of WDR5 (WD repeat domain 5) with peptide regions of MLL and Histone 3 that potently binds to WDR5. OICR-9429 inhibits the interaction of WDR5 with MLL1 and RbBP5 in cells. For full characterization details, please see OICR-9429 on the Structural Genomics Consortium (SGC) website.

OICR-0547 is the negative control for the active probe, OICR-9429. To request a sample of the negative control from the SGC, click here.
To learn about other SGC chemical probes for epigenetic targets, visit sigma.com/sgc
 

特点和优势

OICR-9429 is an epigenetic chemical probe available through a partnership with the Structural Genomics Consortium (SGC). To learn more and view other SGC epigenetic probes, visit sigma.com/SGC.
This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
 

其他说明

OICR-9429 has been expertly reviewed and recommended by the Chemical Probes Portal. For more information, please visit the OICR-9429 probe summary on the Chemical Probes Portal website.
 
 

属性

质量水平

100

测定

≥98% (HPLC)

形式

powder

颜色

white to light brown

溶解性

DMSO: 10 mg/mL, clear

储存温度

2-8°C

InChI

1S/C7H5FN2O2/c1-2-3-10-4-5(8)6(11)9-7(10)12/h1,4H,3H2,(H,9,11,12)

InChI key

GMCOGJQJFDQZCP-UHFFFAOYSA-N

 

安全信息

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H315

危险分类

Skin Irrit. 2

储存分类代码

11 - Combustible Solids

WGK

WGK 3

商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 20 | 欧洲Eur. ≥ 16 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 20
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