O-[(乙氧羰基)氰基亚甲基氨基]-N,N,N',N'-四甲基脲四氟硼酸盐，O-[(Ethoxycarbonyl)cyanomethylenamino]-N,N,N',N'-tetramethyluronium tetrafluoroborate [TOTU]；≥99.0% (HPLC)

图片 O-[(乙氧羰基)氰基亚甲基氨基]-N,N,N',N'-四甲基脲四氟硼酸盐，O-[(Ethoxycarbonyl)cyanomethylenamino]-N,N,N',N'-tetramethyluronium tetrafluoroborate [TOTU]；≥99.0% (HPLC)
别名：TOTU, O-[(Ethoxycarbonyl)cyanomethylenamino]-N,N,NÆ,NÆ-tetramethyluronium tetrafluoroborate；8510880025；8510880100； 经验公式（希尔记法）: C10H17BF4N4O3 CAS号: 136849-72-4 分子量: 328.07 MDL编号: MFCD00192127
制造商品牌: 默克 Merck , 西格玛 Sigma-Aldrich
货号（SKU）: 8.51088
CAS号: 136849-72-4
MDL号: MFCD00192127
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¥1,564.17

说明

一般描述

TOTU is an excellent alternative to HOBt-based coupling reagents such as HBTU and TBTU. It has high reactivity and is likely to have low allergenicity and low explosivity. The by-products of using this coupling reagent are water-soluble, making it an ideal choice for solution phase coupling reactions.

Associated Protocols and Technical Articles
Guide to Selection of Coupling Reagents

Literature references

[1] G. Breipohl & W. Koenig, US patent 5166394.

分析说明

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): conforms
Assay (HPLC, area%): ≥ 99.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clear soluble
 

法律信息

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
 
 

属性

质量水平

200

产品线

Novabiochem®

检测方案

≥99.0% (HPLC)

形式

powder

效能

500-650 mg/kg LD50, oral (Rat)

反应适用性

reaction type: Coupling Reactions

制造商/商品名称

Novabiochem®

mp

142-148 °C

应用

peptide synthesis

储存温度

2-8°C

InChI

1S/C10H17N4O3.BF4/c1-6-16-9(15)8(7-11)12-17-10(13(2)3)14(4)5;2-1(3,4)5/h6H2,1-5H3;/q+1;-1

InChI key

FPQVGDGSRVMNMR-UHFFFAOYSA-N

 

安全信息

象形图

CorrosionExclamation mark
GHS05,GHS07

警示用语：

Danger

危险分类

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Sens. 1A - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

 
商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 10 | 欧洲Eur. ≥ 8 | 東京Tokyo ≥ 6 | 香港与北京 ≥ 60
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