MSSK1, active, GST tagged human,PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

别名: MGC102944, SRPK3, STK23 NACRES: NA.32
制造商品牌: 西格玛 Sigma-Aldrich
货号(SKU): M0824
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¥6,753.72

说明

MSSK1,也称为SRPK3,是一种肌肉特异性蛋白激酶,属于丝氨酸精氨酸蛋白激酶家族,其磷酸化含丝氨酸/精氨酸重复的蛋白。心脏和骨骼肌显示MSSK1 / SRPK3基因产物的高表达。SRPK3-null小鼠显示2型纤维特异性肌病的新实体,中心放置的细胞核显着增加。在骨骼肌中过表达SRPK3的转基因小鼠表现出严重的肌纤维变性和早期致死性。

生化/生理作用

MSSK1, also known as SRPK3, is a muscle-specific protein kinase belonging to the serine arginine protein kinase family which phosphorylates serine/arginine repeat-containing proteins. Heart and skeletal muscle show high expression of the MSSK1/SRPK3 gene product. SRPK3-null mice display a new entity of type 2 fiber-specific myopathy with a marked increase in centrally placed nuclei. Transgenic mice overexpressing SRPK3 in skeletal muscle show severe myofiber degeneration and early lethality.
 

外形

Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.
 

法律信息

PRECISIO is a registered trademark of Sigma-Aldrich Co. LLC
 
 

属性

重组

expressed in baculovirus infected Sf9 cells

质量水平

产品线

PRECISIO® Kinase

测定

≥70% (SDS-PAGE)

形式

buffered aqueous glycerol solution

specific activity

200-270 nmol/min·mg

分子量

~98 kDa

UniProt登记号

运输

dry ice

储存温度

−70°C

Gene Information

human ... SRPK3(26576)

 

安全信息

储存分类代码

10 - Combustible liquids

WGK

WGK 1

商品规格
属性名称属性值
储存温度 Storage temp.-70°C超低温冷冻
全球实时库存 Availability √美国St. Louis ≥ 20 | 欧洲Eur. ≥ 16 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 20