L-(-)-岩藻糖,L-(−)-Fucose;≥99%

别名:6-脱氧-L-半乳糖,L-岩藻糖,6-脱氧-L-半乳糖,墨角澡糖,L-夫糖,L-去氧水解乳糖,L-脱氧半乳糖,F2252-5G-9,6-Deoxy-L-galactose

Empirical Formula (Hill Notation): C6H12O5 CAS号: 2438-80-4 分子量: 164.16 Beilstein: 1723321 EC 号: 219-452-7 MDL编号: MFCD00135607 PubChem化学物质编号: 24894816 NACRES: NA.25
制造商品牌: 西格玛 Sigma-Aldrich
货号(SKU): F2252
CAS号: 2438-80-4
MDL号: MFCD00135607
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¥950.00

说明

L-岩藻糖是哺乳动物中发现的一种天然单糖,是几种N-和O-连接的聚糖和糖脂的重要组成部分。
L-岩藻糖(6-脱氧-L-半乳糖)用于含聚糖的岩藻多糖的研究。它被研究为一种聚糖修饰碳水化合物,产生IgE抗体识别的抗原位点。L-岩藻糖被用作鉴定、区分和表征岩藻糖苷酶、L-岩藻糖苷异构酶和L-岩藻葡萄糖脱氢酶等酶的底物。它可用于研究细胞器和细菌微腔,参与植物和藻类细胞壁糖的降解。L-岩藻糖也可用作稀有糖鉴定和分析的参考化合物。
L-岩藻糖广泛用作食品添加剂。它具有抗炎作用。它可以抑制皮肤免疫反应和肺泡巨噬细胞启动。L-岩藻糖还可以抑制肿瘤生长和肿瘤发生。

一般描述

L-Fucose, a natural monosaccharide found in mammals, is an important component of several N- and O-linked glycans and glycolipids.
 

应用

L-(−)-Fucose has been used:
  • as the non-haptenic sugar in lectin bead-binding assay to study its effects on the binding of immobilized lectins like peanut agglutinin (PNA) and Dolichos biflorus agglutinin (DBA)
  • as an internal standard to dilute the enzymatic hydrolysates for analytical methods
  • in the synthesis of fucosyl thioglycoside

生化/生理作用

L-Fucose (6-Deoxy-L-galactose) is used in studies of fucoidan polysaccharides containing glycans. It is studied as a glycan modifying carbohydrate that generates antigenic sites recognized by IgE antibodies. L-Fucose is used as a substrate to identify, differentiate, and characterize enzymes such as fucosidase(s),l-fucose isomerase(s), and L-fucose dehydrogenase(s). It may be used to study organelles, and bacterial microcompartments, involved in the degradation of plant and algal cell wall sugars. L-Fucose may also be used as a reference compound in rare sugar identification and analysis.
L-Fucose is broadly used as a food additive. It possesses anti-inflammatory effects. It can inhibit the cutaneous immune reaction and alveolar macrophage priming. L-fucose can also suppress tumor growth and tumorigenesis.
 
 

属性

质量水平

测定

≥99%

形式

powder

technique(s)

gas chromatography (GC): suitable

mp

150-153 °C (lit.)

溶解性

H2O: soluble 50 mg/mL, clear to very slightly hazy

SMILES string

C[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)C=O

InChI

1S/C6H12O5/c1-3(8)5(10)6(11)4(9)2-7/h2-6,8-11H,1H3/t3-,4+,5+,6-/m0/s1

InChI key

PNNNRSAQSRJVSB-KCDKBNATSA-N

 

安全信息

储存分类代码

11 - Combustible Solids

WGK

WGK 3

个人防护装备

Eyeshields, Gloves, type N95 (US)

商品规格
属性名称属性值
储存温度 Storage temp.常温阴凉避光
全球实时库存 Availability √美国St. Louis ≥ 20 | 欧洲Eur. ≥ 16 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 20
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