ISOX-INACT，≥98% (HPLC)

别名：4-(2-(5-(3,5-二甲基异恶唑-4-基)-2-(4-甲氧基苯乙基)-4,6-二甲基-1H苯并[d]咪唑-1-基)乙基)吗啉；4-(2-(5-(3,5-Dimethylisoxazol-4-yl)-2-(4-methoxyphenethyl)-4,6-dimethyl-1Hbenzo[d]imidazol-1-yl)ethyl)morpholine

Empirical Formula (Hill Notation): C29H36N4O3 分子量: 488.62 PubChem化学物质编号: 329823843 NACRES: NA.77

制造商品牌: 西格玛 Sigma-Aldrich

货号（SKU）: PZ0332

CAS号: 1962928-29-5

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目录价.SKU-Variant

5mg
25mg [+¥3,304.12]

¥1,591.58

数量:

说明

生化/生理作用

CBP BRD (CREB binding protein bromodomain) inhibition serves as an effective therapeutic target for Parkinson′s disease. The inhibition is followed by negative regulation of a number of macrophage inflammatory genes. It also downregulates G-protein signaling 4 mRNA.[1]

ISOX-INACT is an inactive control probe for the highly-selective inhibitor of the bromodomain of CREB binding protein (CBP BRD) PF-CBP1.

其他说明

This compound was developed by Pfizer for Gene Regulation research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.

法律信息

Sold for research purposes under agreement from Pfizer Inc.

Pfizer is a registered trademark of Pfizer, Inc.

属性

质量水平

100

测定

≥98% (HPLC)

形式

powder

mfr. no.

Pfizer^®

颜色

white to beige

溶解性

DMSO: 5 mg/mL, clear (warmed)

创始人

Pfizer

储存温度

room temp

SMILES string

CC1=NOC(C)=C1C2=C(C)C(N=C(CCC3=CC=C(OC)C=C3)N4CCN5CCOCC5)=C4C=C2C

InChI

1S/C29H36N4O3/c1-19-18-25-29(20(2)27(19)28-21(3)31-36-22(28)4)30-26(11-8-23-6-9-24(34-5)10-7-23)33(25)13-12-32-14-16-35-17-15-32/h6-7,9-10,18H,8,11-17H2,1-5H3

InChI key

FTOHXUPHICJSCR-UHFFFAOYSA-N

安全信息

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

商品规格

属性名称	属性值
储存温度 Storage temp.	常温阴凉避光
全球实时库存 Availability √	美国St. Louis ≥ 20 \| 欧洲Eur. ≥ 16 \| 東京Tokyo ≥ 5 \| 香港与北京 ≥ 20

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