IQ-1S,≥98% (HPLC)

别名:11H-茚并[1,2-b]喹喔啉-11-酮肟;11H-Indeno[1,2-b]quinoxalin-11-one oxime Sodium; IQ-1 sodium

Empirical Formula (Hill Notation): C15H8N3O · Na CAS号: 23146-22-7 分子量: 269.23 NACRES: NA.77
制造商品牌: 西格玛 Sigma-Aldrich
货号(SKU): SML0605
CAS号: 23146-22-7
MDL号: MFCD00612483
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¥1,350.00

说明

生化/生理作用

IQ-1S is an inhibitor of JNK kinases, with a preference for JNK3. Kd values for IQ-3 binding to JNK 1, 2 and 3 binding are 390, 360 and 87 nM, respectively. The compound inhibits JNK phosphorylation and NFkB /AP-1 transcriptional activity in human monocytic cells at low mM concentrations, and inhibits CD4+ T-cell immune response in a murine delayed-type hypersensitivity (DTH) model.
 

特点和优势

This compound is featured on the MAPKs page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
 
 

属性

检测方案

≥98% (HPLC)

形式

powder

颜色

white to beige

溶解性

DMSO: 2 mg/mL, clear (warmed)

储存温度

2-8°C

 

安全信息

监管信息

详询北实纵横科学公司
商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 50 | 欧洲Eur. ≥ 12 | 東京Tokyo ≥ 20 | 香港与北京 ≥ 50