D-(+)-海藻糖二水合物，D-(+)-Trehalose dihydrate；for microbiology, ≥99.0%

别名：α,α-海藻糖；α-D-吡喃葡萄糖基-α-D-吡喃葡萄糖苷；二水海藻糖；D(＋)-蕈糖；蕈糖；D-海藻糖二水合物； α,α-Trehalose, α-D-Glucopyranosyl-α-D-glucopyranoside

Empirical Formula (Hill Notation): C12H22O11 · 2H2O CAS号: 6138-23-4 分子量: 378.33 Beilstein: 5322018 EC 号: 202-739-6 MDL编号: MFCD00071594 PubChem化学物质编号: 329769859 NACRES: NA.85

制造商品牌: 密理博 Millipore , 西格玛 Sigma-Aldrich

货号（SKU）: 90210

CAS号: 6138-23-4

MDL号: MFCD00071594

签订合同 √ 正规发票 √ 技术支持 √ 质量保障 √ 全程可追溯 √

目录价.SKU-Variant

50g
250g [+¥9,703.58]

¥4,158.68

数量:

说明

D-（+）-海藻糖是由两个α-葡萄糖单元组成的二糖。它被用作多种细胞冷冻介质中的冷冻保护剂。在运输介质中用作保护剂。它主要存在于支持脱水症（无水生活）的物种中。它作为微生物中的碳水化合物储备，保护它们免受不利条件的影响，如热、冷、脱水、干燥和氧化。海藻糖作为影响蛋白质折叠的化学伴侣。已知在体外可防止淀粉样蛋白的生成和β-淀粉样蛋白积累。海藻糖对亨廷顿舞蹈症蛋白聚集也有类似的作用。因此，它可以作为阿尔茨海默病和亨廷顿病的保护剂。海藻糖刺激沙门氏菌细胞更好的初始生长。
D-（+）-海藻糖可以用作某些细胞培养中的碳水化合物储备，以克服环境压力。它也可用于生物制药单克隆抗体制剂和蛋白质稳定剂。

一般描述

D-(+)-Trehalose is a disaccharide composed of two α-glucose units. It is used as a cryoprotectant in a variety of cell freezing media. Used as a protectant in transportation media. It predominantly exists among the species that support anhydrobiosis (life without water). It serves as a carbohydrate reserve in microorganisms and protects them from adverse conditions, such as heat, cold, dehydration, desiccation, and oxidation. Trehalose acts as a chemical chaperone affecting protein folding. It is known to prevent the generation of amyloids and accumulation of β-amyloid in vitro. A similar effect of trehalose has been observed with Huntingtin protein aggregation. Thus, it might serve as a protective agent in Alzheimer′s disease and Huntington′s disease. Trehalose stimulates the better initial growth of Salmonella cells.

应用

D-(+)-Trehalose can be used as a carbohydrate reserve in certain cell cultures to tide over environmental stresses. It can also be used in biopharmaceutical monoclonal antibody formulations and as a protein stabilizer.

属性

质量水平

200

测定

≥99.0% (HPLC)
≥99.0%

形式

powder

旋光性

[α]20/D +176 to +186°, c = 2% in H₂O

分子量

378.33 g/mol

杂质

≤0.1% glucose

灼烧残渣

≤0.1% (as SO₄)

溶解性

H₂O: 0.1 g/mL, clear, colorless

痕量阴离子

chloride (Cl^-): ≤50 mg/kg
sulfate (SO₄^2-): ≤50 mg/kg

痕量阳离子

As: ≤0.1 mg/kg
Ca: ≤200 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Mg: ≤10 mg/kg
Mn: ≤5 mg/kg
Na: ≤50 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤10 mg/kg

application(s)

microbiology

SMILES string

[H]O[H].[H]O[H].OC[C@H]1O[C@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C12H22O11.2H2O/c13-1-3-5(15)7(17)9(19)11(21-3)23-12-10(20)8(18)6(16)4(2-14)22-12;;/h3-20H,1-2H2;2*1H2/t3-,4-,5-,6-,7+,8+,9-,10-,11-,12-;;/m1../s1

InChI key

DPVHGFAJLZWDOC-PVXXTIHASA-N

安全信息

储存分类代码

11 - Combustible Solids

WGK

WGK 1

个人防护装备

Eyeshields, Gloves, type N95 (US)

商品规格

属性名称	属性值
储存温度 Storage temp.	常温阴凉避光
全球实时库存 Availability √	美国St. Louis ≥ 10 \| 欧洲Eur. ≥ 8 \| 東京Tokyo ≥ 6 \| 香港与北京 ≥ 60

商品标签 [tags]

d-海藻糖二水合物 (7)