CP-945598,≥98% (HPLC)

别名:Otenabant hydrochloride;CP-945,598;CP 945598-01;1-[8-(2-氯苯基)-9-(4-氯苯基)-9H-嘌呤-6-基]-4-乙氨基-4-哌啶甲酰胺盐酸盐;1-[9-(4-氯苯基)-8-(2-氯苯基)-9H-嘌呤-6-基]-4-乙氨基哌啶-4-羧酸酰胺盐酸盐;1-[8-(2-Chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]-4-(ethylamino)-4-piperidinecarboxamide hydrochloride;1-[9-(4-Chlorophenyl)-8-(2-chlorophenyl)-9H-purin-6-yl]-4-ethylaminopiperidine-4-carboxylic acid amide hydrochloride

Empirical Formula (Hill Notation): C25H25Cl2N7O · HCl CAS号: 686347-12-6 分子量: 546.88
制造商品牌: 西格玛 Sigma-Aldrich
货号(SKU): PZ0019
CAS号: 686347-12-6
MDL号: MFCD18251544
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¥1,090.45

说明

生化/生理作用

CP-945,598 is a potent, selective, high affinity and competitive cannabinoid type 1 (CB1) receptor antagonist. CP-945,598 inhibits both basal and cannabinoid agonist-mediated CB1 receptor signaling in vitro and in vivo. CP-945,598 exhibits anorectic activity in two models of acute food intake in rodents, fast-induced re-feeding and spontaneous, nocturnal feeding.
CP-945,598 is also known as 1-(8-(2-Chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl)-4-(ethylamino)piperidine-4-carboxamide. This orally active antagonist of the cannabinoid CB-1 receptor may be used in the treatment of obesity.[1]
 

特点和优势

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
 

其他说明

This compound was developed by Pfizer for Neuroscience research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.
To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
 

法律信息

Sold for research purposes under agreement from Pfizer Inc.
Pfizer is a registered trademark of Pfizer, Inc.
 
 

属性

质量水平

100

测定

≥98% (HPLC)

形式

powder

mfr. no.

Pfizer®

颜色

white to beige

溶解性

DMSO: 1 mg/mL, clear (warmed)

创始人

Pfizer

储存温度

room temp

 

安全信息

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

商品规格
属性名称属性值
储存温度 Storage temp.常温阴凉避光
全球实时库存 Availability √美国St. Louis ≥ 20 | 欧洲Eur. ≥ 16 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 20