CIL56 [CA3];≥97% (HPLC)

别名:2,7-双(哌啶-1-基磺酰基)-9H-芴-9-酮肟;1,1'-[[9-(羟基亚氨基)-9H-芴-2,7-二基]双(磺酰基)]双哌啶;2,7-双(1-哌啶基磺酰基)-9H-芴-9-一 肟;1,1′-[[9-(Hydroxyimino)-9H-fluorene-2,7-diyl]bis(sulfonyl)]bis-piperidine;2,7-bis(1-Piperidinylsulfonyl)-9H-fluoren-9-one oxime;CIL56

Empirical Formula (Hill Notation): C23H27N3O5S2 CAS号: 300802-28-2 分子量: 489.61 MDL编号: MFCD00323348
制造商品牌: 西格玛 Sigma-Aldrich
货号(SKU): SML2647
CAS号: 300802-28-2
MDL号: MFCD00323348
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¥916.43

说明

生化/生理作用

CA3 is a potent and selective inhibitor of YAP1 (Hippo co-activator Yes-associated protein 1) that inhibits YAP1 expression and transcriptional activity in esophageal adenocarcinoma (EAC) cell lines. CA3 potently inhibits growth, induces apoptosis in radiation resistant CSC (cancer stem cell) enriched EAC cells. It inhibits tumor growth of in xenograft model with no apparent toxicity.
 
 

属性

检测方案

≥97% (HPLC)

形式

powder

颜色

white to beige

溶解性

DMSO: 2 mg/mL, clear

储存温度

−20°C

 

安全信息

储存分类代码

11 - Combustible Solids

WGK

WGK 3

商品规格
属性名称属性值
储存温度 Storage temp.-20°C低温冷冻
全球实时库存 Availability √美国St. Louis ≥ 20 | 欧洲Eur. ≥ 16 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 20
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