4-氨基-1-叔丁基-3-(1'-萘基)吡唑并[3,4-d]嘧啶，4-Amino-1-tert-butyl-3-(1’-naphthyl)pyrazolo[3,4-d]pyrimidine [1-NA-PP1, PP1 Analog]

图片 4-氨基-1-叔丁基-3-(1'-萘基)吡唑并[3,4-d]嘧啶，4-Amino-1-tert-butyl-3-(1’-naphthyl)pyrazolo[3,4-d]pyrimidine [1-NA-PP1, PP1 Analog]
CasNo：221243-82-9；分子式:C19H19N5；分子量:317.3877
制造商品牌: 加拿大TRC
货号（SKU）: A603004
CAS号: 221243-82-9
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Product Description

Catalogue NumberA603004
Chemical Name4-Amino-1-tert-butyl-3-(1’-naphthyl)pyrazolo[3,4-d]pyrimidine
Synonyms1-(1,1-Dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine; 1-NA-PP1;
CAS Number221243-82-9
Molecular FormulaC₁₉H₁₉N₅
AppearanceWhite to Off-White Solid
Melting Point215-218°C
Molecular Weight317.39
Storage-20°C Freezer
SolubilityChloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
CategoryStandards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
ApplicationsA highly potent (IC50=1.5nM) and uniquely specific tyrosine kinase inhibitor of a rationally engineered v-Src tyrosine kinase. It is a COVID19-related research product.
ReferencesBishop, A.C., et al.: J. Am. Chem. Soc., 121, 627 (1999), Davies, S., et al.: Biochem. J., 351, 95 (2000), Regan, J., et al.: J. Med. Chem., 45, 2994 (2002), Bain, J., et al.: Biochem. J., 371, 199 (2003), Kuma, Y., et al.: J. Biol. Chem., 280, 19472 (2005),
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储存温度 Storage temp.-20°C低温冷冻
全球实时库存 Availability √美国St. Louis ≥ 20 | 欧洲Eur. ≥ 16 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 20
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