3,4-二-O-咖啡酰奎宁酸，3,4-Di-O-caffeoylquinic acid [3,4-COQ]；≥90% (LC/MS-ELSD)

图片 3,4-二-O-咖啡酰奎宁酸，3,4-Di-O-caffeoylquinic acid [3,4-COQ]；≥90% (LC/MS-ELSD)
别名：4,5-二咖啡酰奎尼酸；3,4-二-O-咖啡酰奎尼酸；3,4-二咖啡酰奎尼酸（CAS）；异绿原酸B；4,5-Dicaffeoylquinic acid；3,4-Di-O-caffeoylquinic acid；3,4-Dicaffeoylquinic acid (CAS)；Isochlorogenic acid B

Empirical Formula (Hill Notation): C25H24O12 CAS号: 14534-61-3 分子量: 516.45 MDL编号: MFCD22375481 PubChem化学物质编号: 329824881 NACRES: NA.25
制造商品牌: 西格玛 Sigma-Aldrich
货号（SKU）: SMB00224
CAS号: 14534-61-3
MDL号: MFCD22375481
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说明

3,4-Di-O-caffeoylquinic acid 是药草 Youngia japonica 的一种成分。
3,4-COQ 在其结构中具有与六环奎尼酸相连的咖啡酰部分。

3,4-COQ 引发抗氧化作用，介导其对体外视网膜损伤的神经保护作用。 它还对骨髓来源的间充质干细胞 (bmMSCs) 的氧化损伤发挥细胞保护作用。

3,4-二-O-咖啡酰奎尼酸以及 3,5-二咖啡酰奎尼酸和木犀草素-7-O-葡萄糖苷是药草 Youngia japonica 的成分。 它具有已知的抗病毒活性，并且与 3,5,-二咖啡酰奎宁酸一起，显示出抗呼吸道合胞病毒 (RSV) 的活性。

一般描述

3,4-Di-O-caffeoylquinic acid is a component of the medicinal herb Youngia japonica.
3,4-COQ has a caffeoyl moiety attached with a hexacyclic quinic acid in its structure.
 

应用

3,4-Di-O-caffeoylquinic acid has been used as a reference standard:
  • to quantify the caffeoylquinic acids of Artemisia frigida Willd. (Fringed sagewort) using high-performance liquid chromatography with diode array detection and electrospray ionization triple quadrupole mass spectrometric detection (HPLC-DAD-ESI-QQQ-MS)
  • to quantify the phenolic compounds of Artemisia species using high-performance liquid chromatography with diode array detection (HPLC-DAD) technique
  • for metabolic profiling of methanolic leaf extract of A. nallamalayana and to identify the phenolic acids using High-Performance Liquid Chromatography-Ultraviolet (HPLC-UV) analysis

生化/生理作用

3,4-COQ elicits antioxidant effects which mediate its neuroprotective effects against in vitro retinal damage. It also exerts cytoprotective effects against oxidative damage in bone marrow-derived mesenchymal stem cells (bmMSCs).
3,4-Di-O-caffeoylquinic acid, along with 3,5-dicaffeoylquinic acid and luteolin-7-O-glucoside, is a component of the medicinal herb Youngia japonica. It has known antiviral activity and along with 3,5,-dicaffeoylquinic acid, shows activity against respiratory syncyntial virus (RSV).
 
 

属性

质量水平

200

测定

≥90% (LC/MS-ELSD)

形式

solid

储存温度

−20°C

SMILES string

O[C@@H]1C[C@](O)(C[C@@H](OC(=O)\C=C\c2ccc(O)c(O)c2)[C@@H]1OC(=O)\C=C\c3ccc(O)c(O)c3)C(O)=O

InChI

1S/C25H24O12/c26-15-5-1-13(9-17(15)28)3-7-21(31)36-20-12-25(35,24(33)34)11-19(30)23(20)37-22(32)8-4-14-2-6-16(27)18(29)10-14/h1-10,19-20,23,26-30,35H,11-12H2,(H,33,34)/b7-3+,8-4+/t19-,20-,23-,25+/m1/s1

InChI key

UFCLZKMFXSILNL-PSEXTPKNSA-N

 

安全信息

储存分类代码

11 - Combustible Solids

WGK

WGK 3

商品规格
属性名称属性值
储存温度 Storage temp.-20°C低温冷冻
全球实时库存 Availability √美国St. Louis ≥ 30 | 欧洲Eur. ≥ 10 | 東京Tokyo ≥ 9 | 香港与北京 ≥ 30
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