3,3',4,4'-四溴联苯，3,3',4,4'-Tetrabromobiphenyl [PBB 77]

图片 3,3',4,4'-四溴联苯，3,3',4,4'-Tetrabromobiphenyl [PBB 77]
别名：3,3',4,4'-四溴-1,1'-联苯；3,4,3',4'-四溴联苯；多溴联苯77；3,3',4,4'-Tetrabromo-1,1'-biphenyl；3,4,3',4'-Tetrabromobiphenyl；PBB 77
制造商品牌: 加拿大TRC
货号（SKU）: T291333
CAS号: 77102-82-0
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Product Description

Catalogue NumberT291333
Chemical Name3,3',4,4'-Tetrabromobiphenyl
Synonyms3,3',4,4'-Tetrabromo-1,1'-biphenyl; 3,4,3',4'-Tetrabromobiphenyl; PBB 77;
CAS Number77102-82-0
Molecular FormulaC₁₂H₆Br₄
AppearancePale Brown Solid
Melting Point>123°C (dec.)
Molecular Weight469.79
StorageRoom Temperature
SolubilityChloroform (Slightly), Methanol (Slightly)
CategoryStandards; Pharmaceutical/API Drug Impurities/Metabolites; Environmental Standards, Mutagens and Metabolites;
Applications3,3',4,4'-Tetrabromobiphenyl is multi-persistent organic pollutants analyzed in breast milk of first time mothers. An environmental pollutant that affects copper and molybdenum metabolism in rats. Also, it is derived from 1-Bromo-2- nitrobenze (B686175), which is an organic building block used for the synthesis of various pharmaceutical compounds. It is an intermediate for the synthesis of novel Diarylamino-1,3,5-triazine derivatives as FAK inhibitors with anti-angiogenic activity.
ReferencesTlustos, C., et al.: Organohalogen Compd., 75, 1185-1188 (2013); Salman, K. N., et al.: Environ. Sci. Pollut. R., 21, 6400-6409 (2014); Dao, P., et al.: Bioorg. Med. Chem. Lett., 23, 4552 (2013);
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