1H-苯并三唑-1-基氧三吡咯烷基六氟磷酸盐，(Benzotriazol-1-yloxy) tripyrrolidinophosphonium hexafluorophosphate [PyBOP]；purum, ≥97.0% (TLC)

别名：六氟磷酸苯并三唑-1-基-氧基三吡咯烷基磷；苯并三唑-1-基氧三吡咯烷基鏻六氟磷酸；1H-苯并三唑-1-氧三吡咯啉嗡六氟磷酸；8510090025；8510090100

线性分子式: C18H28N6OP · PF6 CAS号: 128625-52-5 分子量: 520.39 Beilstein: 3584612 MDL编号: MFCD00077411 PubChem化学物质编号: 329749882 NACRES: NA.22

制造商品牌: 西格玛 Sigma-Aldrich

货号（SKU）: 12805

CAS号: 128625-52-5

MDL号: MFCD00077411

签订合同 √ 正规发票 √ 技术支持 √ 质量保障 √ 全程可追溯 √

¥718.04

数量:

说明

（苯并三唑-1-羟基）三吡咯烷磷酸二氟磷酸酯（PYBOP）是在肽合成中常用的羧基的激活剂。它还参与羧酸酯化。它显示了类似于苯并三唑-1-氯氧基）Tris（二甲基氨基）六氟磷酸磷（BOP）的特征，可以用作肽键形成中BOP的替代方案。

一般描述

(Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate (PyBOP) is an activator of carboxyl group commonly used in peptide synthesis. It also participates in the carboxylic acid esterification. It shows characteristics similar to benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate (BOP) and can be utilized as an alternative to BOP in peptide bond formation.

应用

(Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate (PyBOP) may be used in the following studies:

As coupling reagent in the preparation strategies for peptide-oligonucleotide conjugates.
Synthesis of structured pure triacylglycerol (TAG) regioisomers.
As coupling reagent in the synthesis of a 3,5-pyrazolidinedione on soluble polyethylene glycol (PEG) polymer support.
Synthesis of herceptin- nanoparticles.

BOP 偶联剂类似物，不产生致癌副产物 HMPA。

法律信息

PyBOP is a registered trademark of Merck KGaA, Darmstadt, Germany

属性

等级

purum

质量水平

200

测定

≥97.0% (TLC)

形式

solid

reaction suitability

reaction type: Coupling Reactions

mp

~150 °C
154-156 °C (dec.) (lit.)

application(s)

peptide synthesis

储存温度

2-8°C

SMILES string

F[P-](F)(F)(F)(F)F.C1CCN(C1)[P+](On2nnc3ccccc23)(N4CCCC4)N5CCCC5

InChI

1S/C18H28N6OP.F6P/c1-2-10-18-17(9-1)19-20-24(18)25-26(21-11-3-4-12-21,22-13-5-6-14-22)23-15-7-8-16-23;1-7(2,3,4,5)6/h1-2,9-10H,3-8,11-16H2;/q+1;-1

InChI key

VIAFLMPQBHAMLI-UHFFFAOYSA-N

安全信息

象形图

GHS07,GHS09

警示用语：

Warning

危险声明

H302 - H317 - H410

预防措施声明

P261 - P264 - P273 - P280 - P301 + P312 - P302 + P352

危险分类

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Skin Sens. 1

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

商品规格

属性名称	属性值
储存温度 Storage temp.	2-8°C冷藏
全球实时库存 Availability √	美国St. Louis ≥ 50 \| 欧洲Eur. ≥ 12 \| 東京Tokyo ≥ 20 \| 香港与北京 ≥ 50

商品标签 [tags]

pybop (3)