Catalogue Number | T947620 |
Chemical Name | (+)-Tubocurarine Chloride Hydrochloride Pentahydrate |
Synonyms | (13aR,25aS)-2,3,13a,14,15,16,25,25a-Octahydro-9,19-dihydroxy-18,29-dimethoxy-1,14,14-trimethyl-13H-4,6:21,24-Dietheno-8,12-metheno-1H-pyrido[3',2':14,15][1,11]dioxacycloeicosino[2,3,4-ij]isoquinolinium Chloride Hydrochloride Hydrate (1:1:1:5); 7',12'-dihydroxy-6,6'-dimethoxy-2,2',2'-trimethyltubocuraranium Chloride Hydrochloride Pentahydrate; Tubarine Pentahydrate; d-Tubocurarine Dichloride Pentahydrate; |
CAS Number | 6989-98-6 |
Alternate CAS # | 57-95-4 Chloride Hydrochloride |
Molecular Formula | C37H52Cl2N2O11 |
Appearance | Off-White Solid |
Melting Point | >231°C (dec.) |
Molecular Weight | 771.72 |
Storage | Hygroscopic, -20°C Freezer, Under inert atmosphere |
Solubility | Methanol (Slightly), Water (Slightly, Heated) |
Stability | Hygroscopic |
Category | Research Tools; Pharmaceutical/API Drug Impurities/Metabolites; |
Applications | (+)-Tubocurarine Chloride, is a a long-duration antagonist for nicotinic acetylcholine receptor, used widely in anesthesia to provide skeletal muscle relaxation during surgery or mechanical ventilation. |
| Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package |
References | Bren, N., et al.: J. Biol. Chem., 272, 30793 (1997); Fu, D.X., et al.: J. Biol. Chem., 269 (1994); Gronert, G.A.,et al.L J, App. Physiol. Resprat. Envrion. Exercise. Physiol., 57, 1502 (1984); Hughes, R., et al.: Brit. J. Anaesthesia., 48, 847 (1976); |