落新妇苷,Astilbin from Engelhardtia roxburghiana;≥98%

别名:落新妇甙;紫杉叶素3-鼠李糖苷;二氢槲皮素3-鼠李糖苷;落新妇苷;Astilbin, Dihydroquercetin 3-rhamnoside, Taxifolin 3-rhamnoside

Empirical Formula (Hill Notation): C21H22O11 CAS号: 29838-67-3 分子量: 450.39 MDL编号: MFCD20274680 NACRES: NA.25
制造商品牌: 西格玛 Sigma-Aldrich
货号(SKU): A2862
CAS号: 29838-67-3
MDL号: MFCD20274680
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¥1,468.74

说明

落新妇苷属于二氢黄烷醇类化合物,是土茯苓 (RSG) 提取物的主要生物活性成分。 RSG 是从 Smilax Glabra Roxb 的干燥根茎中获得的。

来自 Engelhardtia roxburghiana 的落新妇苷是一种具有抗菌活性的类黄酮植物化学物质,可用于研究其药理学及其抗增殖活性对多种细胞类型的影响。

落新妇苷发挥多种生物活性,如抗氧化、抗菌和抑制接触过敏。此外,它还具有杀虫、抗水肿、镇痛和抗抑郁的特性。对醛糖还原酶、山梨醇的蓄积有抑制作用,对肝脏有保护作用。落新妇苷有助于对抗类风湿性关节炎等自身免疫性疾病,因为它能够降低 T 淋巴细胞中的基质金属蛋白酶 (MMP) 活性和一氧化氮的产生。
在圣约翰草和中药草药制剂中发现的黄酮类植物化学物质。免疫抑制。抗增殖。

一般描述

Astilbin belongs to the class of dihydroflavanol compounds and is the chief biologically active component of Rhizoma Smilacis Glabrae (RSG) extract. RSG is obtained from the dried rhizome of Smilax Glabra Roxb.
 

应用

Astilbin from Engelhardtia roxburghiana, a flavonoid phytochemical with antibacterial activity, may be used to study its pharmacology and the effects of its antiproliferative activities versus a variety of cell types.
 

生化/生理作用

Astilbin exerts various biological activities such as anti-oxidative, anti-bacterial, and inhibition of contact hypersensitivity. Also, it shows insecticidal, anti-oedematogenic, antinociceptive and antidepressant properties. It has an inhibitory effect on the aldose reductase enzyme, the accumulation of sorbitol, and a protective effect on the liver. Astilbin is helpful against autoimmune diseases such as rheumatoid arthritis due to its ability to reduce matrix metalloproteinase (MMP) activity and Nitric oxide production in T lymphocytes.
Flavonoid phytochemical found in St. John′s wort and Traditional Chinese Medicine herbal preparations. Immunosuppresive. Antiproliferative.
 
 

属性

质量水平

100

测定

≥98%

形式

powder

溶解性

H2O: 1 mg/mL, clear, colorless

储存温度

2-8°C

SMILES string

O=C1C2=C(O)C=C(O)C=C2O[C@H](C3=CC(O)=C(O)C=C3)[C@H]1O[C@@]4([H])[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O4

InChI

1S/C21H22O11/c1-7-15(26)17(28)18(29)21(30-7)32-20-16(27)14-12(25)5-9(22)6-13(14)31-19(20)8-2-3-10(23)11(24)4-8/h2-7,15,17-26,28-29H,1H3/t7-,15-,17+,18+,19-,20+,21-/m0/s1

InChI key

ZROGCCBNZBKLEL-MFSALPCASA-N

 

安全信息

象形图

Environment

警示用语:

Warning

危险声明

预防措施声明

危险分类

Aquatic Acute 1

储存分类代码

11 - Combustible Solids

WGK

WGK 3

商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 20 | 欧洲Eur. ≥ 16 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 20
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