神经垂体素，PACAP 27 Amide, Ovine；Increases cAMP levels in a dose-dependent manner (EC₅₀ = 4.7 nM).

别名：PACAP 27 Amide, Ovine, Pituitary Adenylate Cyclase Activating Polypeptide, HSDGIFTDSYSRYRKQMAVKKYLAAVL-NH₂

经验公式（希尔记法）: C142H224N40O39S CAS号: 127317-03-7 分子量: 3147.61 MDL编号: MFCD00167418

制造商品牌: 西格玛 Sigma-Aldrich

货号（SKU）: 05-23-2151

CAS号: 127317-03-7

MDL号: MFCD00167418

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目录价.SKU-Variant

1mg
5mg [+¥8,740.00]
25mg [+¥31,540.00]

¥4,760.00

数量:

说明

一般描述

Increases cAMP levels in a dose-dependent manner (EC₅₀ = 4.7 nM). Increases tyrosine hydroxylase expression in chromaffin cells.

生化/生理作用

Cell permeable: no

EC50 = 4.7 nM increasing cAMP levels in a dose-dependent manner

Primary Target
Increases cAMP levels

Product does not compete with ATP.

Reversible: no

包装

Yes

警告

Toxicity: Standard Handling (A)

序列

H-His-Ser-Asp-Gly-Ile-Phe-Thr-Asp-Ser-Tyr-Ser-Arg-Tyr-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Ala-Ala-Val-Leu-NH₂

外形

Supplied as a trifluoroacetate salt.

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

其他说明

Kobayashi, H., et al. 1994. Brain Res.647, 145.
Tatsuno, I., et al. 1990. Biochem. Biophys. Res. Commun. 168, 1027.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

属性

质量水平

100

检测方案

≥97% (HPLC)

形式

solid

制造商/商品名称

Calbiochem^®

储存条件

OK to freeze
desiccated (hygroscopic)

颜色

white to off-white

溶解性

5% acetic acid: 1 mg/mL

运输

ambient

储存温度

−20°C

InChI

1S/C142H224N40O39S/c1-16-75(10)113(179-108(191)66-156-120(201)102(63-109(192)193)173-135(216)104(67-183)176-119(200)88(146)62-84-65-153-70-157-84)139(220)174-101(58-80-28-18-17-19-29-80)133(214)182-114(79(14)186)140(221)175-103(64-110(194)195)132(213)178-106(69-185)136(217)172-100(61-83-39-45-87(189)46-40-83)131(212)177-105(68-184)134(215)164-93(34-27-54-155-142(151)152)126(207)170-98(59-81-35-41-85(187)42-36-81)129(210)163-92(33-26-53-154-141(149)150)124(205)161-89(30-20-23-50-143)122(203)165-94(47-48-107(147)190)127(208)166-95(49-55-222-15)121(202)159-78(13)118(199)180-111(73(6)7)137(218)167-91(32-22-25-52-145)123(204)162-90(31-21-24-51-144)125(206)171-99(60-82-37-43-86(188)44-38-82)130(211)169-97(57-72(4)5)128(209)160-76(11)116(197)158-77(12)117(198)181-112(74(8)9)138(219)168-96(115(148)196)56-71(2)3/h17-19,28-29,35-46,65,70-79,88-106,111-114,183-189H,16,20-27,30-34,47-64,66-69,143-146H2,1-15H3,(H2,147,190)(H2,148,196)(H,153,157)(H,156,201)(H,158,197)(H,159,202)(H,160,209)(H,161,205)(H,162,204)(H,163,210)(H,164,215)(H,165,203)(H,166,208)(H,167,218)(H,168,219)(H,169,211)(H,170,207)(H,171,206)(H,172,217)(H,173,216)(H,174,220)(H,175,221)(H,176,200)(H,177,212)(H,178,213)(H,179,191)(H,180,199)(H,181,198)(H,182,214)(H,192,193)(H,194,195)(H4,149,150,154)(H4,151,152,155)

InChI key

RZGBUJXSKLDAFE-UHFFFAOYSA-N

安全信息

储存分类代码

11 - Combustible Solids

WGK

WGK 3

商品规格

属性名称	属性值
储存温度 Storage temp.	-20°C低温冷冻
全球实时库存 Availability √	美国St. Louis ≥ 50 \| 欧洲Eur. ≥ 12 \| 東京Tokyo ≥ 20 \| 香港与北京 ≥ 50

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