硫酸阿托品一水合物，Atropine sulfate salt monohydrate；Pharmaceutical Secondary Standard; Certified Reference Material

别名：阿托品硫酸盐一水合物；龙葵碱；(8-甲基-8-氮杂双环[3.2.1]辛-3-基) edno-(+/-)-α-(羟甲基)苯乙酸酯；硫酸颠茄碱；硫酸DL-莨菪碱；Tropine tropate, α-(Hydroxymethyl)benzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester

线性分子式: (C17H23NO3)2 · H2SO4 · H2O CAS号: 5908-99-6 分子量: 694.83 Beilstein: 6109275 EC 号: 200-235-0 MDL编号: MFCD00074815 PubChem化学物质编号: 329823356 NACRES: NA.24

制造商品牌: 色谱科 Supelco , 西格玛 Sigma-Aldrich

货号（SKU）: PHR1379

CAS号: 5908-99-6

MDL号: MFCD00074815

签订合同 √ 正规发票 √ 技术支持 √ 质量保障 √ 全程可追溯 √

目录价.SKU-Variant

¥1,576.00

数量:

说明

用于质量控制的药物二级标准，为制药实验室和制造商提供了一种方便且具有成本效益的替代方法来制备内部工作标准。
阿托品硫酸盐是一种从颠茄中提取的生物碱。它是一种胆碱能药物，用作抗心律失常药物。

硫酸阿托品可用作药物参考标准，用于通过电泳和色谱技术测定药物制剂中的分析物。

一般描述

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Atropine Sulfate is an alkaloid extracted from belladonna herb. It is a cholinergic drug, administered as an anti-arrhythmic medicine.

应用

Atropine Sulfate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by electrophoresis and chromatography techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

生化/生理作用

位于中枢和外周毒蕈碱型乙酰胆碱受体处的竞争性非选择性拮抗剂。

附注

To see an example of a Certificate of Analysis for this material enter LRAC4087 in the slot below. This is an example certificate only and may not be the lot that you receive.

属性

质量水平

300

等级

certified reference material
pharmaceutical secondary standard

Agency

traceable to BP 23
traceable to Ph. Eur. A1400000
traceable to USP 1045009

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

189-192 °C (A) (lit.)

application(s)

pharmaceutical (small molecule)

格式

neat

储存温度

2-8°C

SMILES string

O.OS(O)(=O)=O.CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)C(CO)c3ccccc3.CN4[C@H]5CC[C@@H]4C[C@@H](C5)OC(=O)C(CO)c6ccccc6

InChI

1S/2C17H23NO3.H2O4S.H2O/c2*1-18-13-7-8-14(18)10-15(9-13)21-17(20)16(11-19)12-5-3-2-4-6-12;1-5(2,3)4;/h2*2-6,13-16,19H,7-11H2,1H3;(H2,1,2,3,4);1H2/t2*13-,14+,15+,16?;;

InChI key

JPKKQJKQTPNWTR-CHYDPLAESA-N

Gene Information

human ... CHRM1(1128) , CHRM2(1129) , CHRM3(1131)

安全信息

象形图

GHS06

警示用语：

Danger

危险声明

H300 + H330

预防措施声明

P301 + P310 + P330 - P304 + P340 + P310

危险分类

Acute Tox. 2 Inhalation - Acute Tox. 2 Oral

储存分类代码

6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

个人防护装备

Eyeshields, Faceshields, Gloves, type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges

商品规格

属性名称	属性值
储存温度 Storage temp.	2-8°C冷藏
全球实时库存 Availability √	美国St. Louis ≥ 50 \| 欧洲Eur. ≥ 12 \| 東京Tokyo ≥ 20 \| 香港与北京 ≥ 50

商品标签 [tags]

硫酸阿托品一水合物 (2)