硫柳汞钠，Thimerosal；Pharmaceutical Secondary Standard; Certified Reference Material

图片 硫柳汞钠，Thimerosal；Pharmaceutical Secondary Standard; Certified Reference Material
别名：硫柳汞钠标准品；乙基噻吩酸 钠盐；乙汞硫柳酸钠；乙汞硫水杨酸钠盐；2-(Ethylmercuriomercapto)benzoic acid sodium salt, Ethylmercurithiosalicylic acid sodium salt, Mercury-([o-carboxyphenyl]thio)ethyl sodium salt, Sodium ethylmercurithiosalicylate

线性分子式: 2-(C2H5HgS)C6H4CO2Na CAS号: 54-64-8 分子量: 404.81 Beilstein: 8169555 EC 号: 200-210-4 MDL编号: MFCD00013062 PubChem化学物质编号: 329823493 NACRES: NA.24
制造商品牌: 西格玛 Sigma-Aldrich , 色谱科 Supelco
货号（SKU）: PHR1587
CAS号: 54-64-8
MDL号: MFCD00013062
签订合同 √ 正规发票 √ 技术支持 √ 质量保障 √ 全程可追溯 √
¥1,607.78

说明

一般描述

Thimerosal belongs to the group of alkyl mercury compounds, widely used as a preservative in vaccine formulations.[1][2] Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
 

应用

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Thimerosal may be used as a pharmaceutical reference standard for the quantification of the analyte in ophthalmic solutions using spectrophotometric technique.[3]
 

生化/生理作用

硫柳汞是一种巯基（硫醇）氧化剂，能抑制多种巯基依赖性酶和蛋白质，如PI3激酶依赖性蛋氨酸合成酶、谷氨酸转运受体和Na++K+依赖性ATP酶。
 

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.
 

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
 

附注

To see an example of a Certificate of Analysis for this material enter LRAA6959 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.
 
 

属性

等级

certified reference material
pharmaceutical secondary standard

质量水平

300

Agency

traceable to Ph. Eur. Y0000109
traceable to USP 1659000

CofA

current certificate can be downloaded

包装

pkg of 1 g

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

234-237 °C (dec.) (lit.)

application(s)

pharmaceutical (small molecule)

格式

neat

储存温度

2-30°C

SMILES string

[Na+].CC[Hg]Sc1ccccc1C([O-])=O

InChI

1S/C7H6O2S.C2H5.Hg.Na/c8-7(9)5-3-1-2-4-6(5)10;1-2;;/h1-4,10H,(H,8,9);1H2,2H3;;/q;;2*+1/p-2

InChI key

RTKIYNMVFMVABJ-UHFFFAOYSA-L

 

安全信息

警示用语：

Danger

危险分类

Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2

储存分类代码

6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

个人防护装备

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

商品规格
属性名称属性值
储存温度 Storage temp.常温阴凉避光
全球实时库存 Availability √美国St. Louis ≥ 50 | 欧洲Eur. ≥ 12 | 東京Tokyo ≥ 20 | 香港与北京 ≥ 50
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