头孢噻肟钠盐 [噻孢霉素],Cefotaxime sodium salt;suitable for plant cell culture, BioReagent, powder or crystals

别名:头孢霉素;头孢赛肟钠盐;头孢噻吩钠盐;Cefotaxim sodium salt;7-[2-(2-Amino-4-thiazolyl)glyoxylamido]-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 7²-(Z)-(O-methyloxime) Acetate, Na, Cefotaxim sodium salt

Empirical Formula (Hill Notation): C16H16N5NaO7S2 CAS号: 64485-93-4 分子量: 477.45 Beilstein: 5711411 EC 号: 264-915-9 MDL编号: MFCD00079073 PubChem化学物质编号: 24892923 NACRES: NA.72
制造商品牌: 西格玛 Sigma-Aldrich
货号(SKU): C7039
CAS号: 64485-93-4
MDL号: MFCD00079073
签订合同 √ 正规发票 √ 技术支持 √ 质量保障 √ 全程可追溯 √
¥985.00

说明

头孢噻肟钠盐已被用作抗生素敏感性试验(AST)方法中的试验抗生素。它也被用作抗生素去除O中的细菌。金牛座文化。
头孢噻肟通过与青霉素结合蛋白(PBP)结合来抑制细菌细胞壁合成,所述青霉素结合蛋白抑制细菌细胞壁中肽聚糖合成的最终转肽步骤。结果,由于细胞壁自溶酶,细菌裂解。
头孢噻肟是一种头孢菌素抗生素,对革兰氏阴性菌和革兰氏阳性菌均有活性。另外,头孢噻肟阻断蓝细菌的分裂。它还具有抑制低等植物细胞器/质体的细胞分裂的能力,例如青光眼植物的光合细胞器和苔藓植物的叶绿体。

一般描述

Chemical structure: ß-lactam
 

应用

Cefotaxime sodium salt has been used as an test antibiotic in antibiotic susceptibility testing (AST) methods. It has also been used as an antibiotic to remove bacteria from O. tauri cultures.
 

生化/生理作用

Cefotaxim inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls. As a result, bacteria lyse due to cell wall autolytic enzymes.
Cefotaxime, a cephalosporin antibiotic, is active against both gram-negative and gram-positive bacteria. In addition, cefotaxime blocks the division of cyanobacteria. It also has an ability to inhibit the cell division of lower plant organelles/plastids such as the photosynthetic organelles of glaucophytes and chloroplasts of bryophytes.
 

其他说明

Broad spectrum third generation cephalosporin antibiotic.
Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place. Keep in a dry place.
 
 

属性

产品线

BioReagent

质量水平

200

形式

powder or crystals

technique(s)

cell culture | plant: suitable

颜色

off-white to pale yellow

溶解性

H2O: 10% ( )

抗生素抗菌谱

Gram-negative bacteria
Gram-positive bacteria

application(s)

agriculture

作用机制

cell wall synthesis | interferes

储存温度

2-8°C

SMILES string

[Na+].[H][C@]12SCC(COC(C)=O)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\c3csc(N)n3)C([O-])=O

InChI

1S/C16H17N5O7S2.Na/c1-6(22)28-3-7-4-29-14-10(13(24)21(14)11(7)15(25)26)19-12(23)9(20-27-2)8-5-30-16(17)18-8;/h5,10,14H,3-4H2,1-2H3,(H2,17,18)(H,19,23)(H,25,26);/q;+1/p-1/b20-9-;/t10-,14-;/m1./s1

InChI key

AZZMGZXNTDTSME-JUZDKLSSSA-M

 

安全信息

象形图

Health hazard

警示用语:

Danger

危险声明

预防措施声明

危险分类

Resp. Sens. 1 - Skin Sens. 1

储存分类代码

13 - Non Combustible Solids

WGK

WGK 2

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 20 | 欧洲Eur. ≥ 16 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 20