匹伐他汀钙，Pitavastatin calcium；≥98% (HPLC)

图片 匹伐他汀钙，Pitavastatin calcium；≥98% (HPLC)
别名：伊伐他汀；(+)monocalcium bis{(3R, 5S, 6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]-3,5dihydroxy-6-heptenoate}, (3R,5S,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic acid calcium salt

Empirical Formula (Hill Notation): C25H23FNO4 · 0.5Ca CAS号: 147526-32-7 分子量: 440.49
制造商品牌: 西格玛 Sigma-Aldrich
货号（SKU）: SML2473
CAS号: 147526-32-7
MDL号: MFCD01937979
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¥620.01

说明

生化/生理作用

Pitavastatin calcium is a water-soluble inhibitor of hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase, the enzyme that catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting step in cholesterol biosynthesis. Pitavastatin calcium is antilipidemic and is used to reduce plasma cholesterol levels and prevent cardiovascular disease.
 
 

属性

检测方案

≥98% (HPLC)

形式

powder

旋光性

[α]/D +19 to +24°, c = 1 in acetonitrile: water (1:1)

储存条件

desiccated

颜色

white to beige

溶解性

DMSO: 2 mg/mL, clear

储存温度

2-8°C

InChI

1S/2C25H24FNO4.Ca/c2*26-17-9-7-15(8-10-17)24-20-3-1-2-4-22(20)27-25(16-5-6-16)21(24)12-11-18(28)13-19(29)14-23(30)31;/h2*1-4,7-12,16,18-19,28-29H,5-6,13-14H2,(H,30,31);/q;;+2/p-2/b2*12-11+;/t2*18-,19-;/m11./s1

InChI key

RHGYHLPFVJEAOC-FFNUKLMVSA-L

 

安全信息

象形图

Health hazard
GHS08

警示用语：

Warning

危险声明

H361f

危险分类

Repr. 2

储存分类代码

11 - Combustible Solids

WGK

WGK 3

商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 50 | 欧洲Eur. ≥ 12 | 東京Tokyo ≥ 20 | 香港与北京 ≥ 50
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