人类热休克蛋白70，Heat Shock Protein 70 human [HSP 70]；recombinant, expressed in E. coli, buffered aqueous solution, ≥90% (SDS-PAGE)

Heat shock protein 70 human has been used as a control for checking antibody reactivity.[1]

 

HSPA8 (heat shock 70kDa protein 8) is a human cytoplasmic chaperone which is involved in protein folding, protein aggregation prevention and protein transport.[2][3] During nutrient stress, it participates in antigen transport to regulate MHC (major histocompatibility) class II presentation.[2] It is upregulated in cancer cells and is involved in protein homeostasis, leading to cancer cell growth and survival.[4]

 

Solution in 2.7 mM KCl, 1.5 mM KH2PO4, 137 mM NaCl, and 8.1 mM Na2HPO4.