Catalogue Number | A777550 |
Chemical Name | Artemisitene |
Synonyms | (3R,5aS,6R,8aS,12S,12aR)-Octahydro-3,6-dimethyl-9-methylene-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10(3H)-one; (+)-Artemisitene; Dehydroqinghaosu; |
CAS Number | 101020-89-7 |
Molecular Formula | C15H20O5 |
Appearance | White to Off-White Solid |
Melting Point | 160-162°C |
Molecular Weight | 280.32 |
Storage | Refrigerator |
Solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
Category | Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites; |
Applications | Artemisitene, the oxidized form of Artemisinin (A777500), exists as a minor constituent in an American variant of Artemisia annua. Artemisinin precursors are the important basic substances for biosynthesis of Artemisinin, including Artemisinic acid, Artemisinin B, Artemisitene, etc. An antimalarial agent. |
References | Li, Y., et al.: Curr. Med. Chem., 10, 2197 (2003), Marrero-Ponce, Y., et al.: Bioorg. Med. Chem., 13, 1293 (2005), McMichael, A., et al.: Lancet, 367, 859 (2006), |