贝曲西班，Betrixaban；≥98% (HPLC)

别名：MK-4448, MLN1021, N-(5-Chloro-2-pyridinyl)-2-[[4-[(dimethylamino)iminomethyl]benzoyl]amino]-5-methoxybenzamide, N-(5-Chloropyridin-2-yl)-2-(4-(N,N-dimethylcarbamimidoyl)benzamido)-5-methoxybenzamide, PRT-054021, PRT054021

Empirical Formula (Hill Notation): C23H22ClN5O3 CAS号: 330942-05-7 分子量: 451.91 MDL编号: MFCD16038040

制造商品牌: 西格玛 Sigma-Aldrich

货号（SKU）: SML2845

CAS号: 330942-05-7

MDL号: MFCD16038040

签订合同 √ 正规发票 √ 技术支持 √ 质量保障 √ 全程可追溯 √

目录价.SKU-Variant

5mg
25mg [+¥2,473.57]
100mg [+¥9,045.62]

¥814.73

数量:

说明

生化/生理作用

Betrixaban is an orally active, active site-targeting, highly potent and selective factor Xa (fXa) inhibitor (IC₅₀ = 1.5 nM; K_i = 117 pM) with much reduced plasma kallikrein inhibitory activity (IC₅₀ = 6.3 μM) and little potency against thrombin, trypsin, t-PA, aPC or plasmin inhibition (IC₅₀ >10 μM). Betrixaban exhibits good pharmacokinetic properties and anticoagulant efficacy against various thromboembolism (VTE) events in vivo.

属性

质量水平

100

检测方案

≥98% (HPLC)

形式

powder

颜色

white to beige

溶解性

DMSO: 2 mg/mL, clear

储存温度

2-8°C

SMILES string

ClC1=CN=C(C=C1)NC(C2=C(NC(C3=CC=C(C(N(C)C)=N)C=C3)=O)C=CC(OC)=C2)=O

InChI

1S/C23H22ClN5O3/c1-29(2)21(25)14-4-6-15(7-5-14)22(30)27-19-10-9-17(32-3)12-18(19)23(31)28-20-11-8-16(24)13-26-20/h4-13,25H,1-3H3,(H,27,30)(H,26,28,31)

InChI key

XHOLNRLADUSQLD-UHFFFAOYSA-N

安全信息

象形图

GHS07,GHS08

警示用语：

Warning

危险声明

H302 - H373

预防措施声明

P301 + P312 + P330 - P314

危险分类

Acute Tox. 4 Oral - STOT RE 2

靶器官

Blood

储存分类代码

11 - Combustible Solids

WGK

WGK 3

商品规格

属性名称	属性值
储存温度 Storage temp.	2-8°C冷藏
全球实时库存 Availability √	美国St. Louis ≥ 50 \| 欧洲Eur. ≥ 12 \| 東京Tokyo ≥ 20 \| 香港与北京 ≥ 50

热门标签