茄尼醇来源于烟草，Solanesol from tobacco；≥90% (HPLC)

图片 茄尼醇来源于烟草，Solanesol from tobacco；≥90% (HPLC)
Empirical Formula (Hill Notation): C45H74O CAS号: 13190-97-1 分子量: 631.07 MDL编号: MFCD00070279 PubChem化学物质编号: 24899813 NACRES: NA.25
制造商品牌: 西格玛 Sigma-Aldrich
货号（SKU）: S8754
CAS号: 13190-97-1
MDL号: MFCD00070279
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说明

茄尼醇主要从烟草（烟草）中提取。它是一种脂肪族萜烯，聚异戊二烯醇。茄尼醇也存在于其他茄科植物中，如番茄（Solanum lycopersicum）、马铃薯（Solanum tuberosum）、茄子、甜椒。这种C45类异戊二烯醇是烟叶中含量最丰富的脂质。

烟草中的茄尼醇已被用作使用反相高效液相色谱 (RP-HPLC) 对不同烟叶样品中茄尼醇进行定量的参考标准。它还被用于提高人工脂质体的稳定性，以测试泛醌 8 (Q8) 介导的大肠杆菌膜在渗透胁迫下的稳定性。

Solanesol 具有抗氧化、抗炎、神经保护和抗菌活性。它还通过与硫代水杨酸 (TS) 和透明质酸 (HA) 结合而作为治疗载体发挥抗癌特性。茄尼醇可能是烟雾中致瘤性多核芳烃的重要前体。

一般描述

Solanesol is mainly extracted from Nicotiana tabacum (tobacco). It is an aliphatic terpene, polyisoprenoid alcohol. Solanesol can also be found in other solanaceous plants such as tomato (Solanum lycopersicum), potato (Solanum tuberosum), eggplant, bell peppers.This C45 isoprenoid alcohol is the most abundant lipid in tobacco leaves.
 

应用

Solanesol from tobacco has been used as a reference standard for the quantification of solanesol from different tobacco leaf samples using reverse-phase high-performance liquid chromatography (RP-HPLC). It has also been used to increase the stability of artificial liposomes to test the mechanical function of ubiquinone-8 (Q8)-mediated membrane stabilization in E. coli under osmotic stress.
 

生化/生理作用

Solanesol displays antioxidant, anti-inflammatory, neuroprotective, and antimicrobial activities. It also exerts anti-cancer properties as a therapeutic carrier by binding together with thiosalicyclic acid (TS) and hyaluronic acid (HA).Solanesol may be an important precursor of the tumorigenic polynuclear aromatic hydrocarbons of smoke.
 
 

属性

质量水平

200

测定

≥90% (HPLC)

形式

powder

储存温度

−20°C

SMILES string

C\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CO

InChI

1S/C45H74O/c1-37(2)19-11-20-38(3)21-12-22-39(4)23-13-24-40(5)25-14-26-41(6)27-15-28-42(7)29-16-30-43(8)31-17-32-44(9)33-18-34-45(10)35-36-46/h19,21,23,25,27,29,31,33,35,46H,11-18,20,22,24,26,28,30,32,34,36H2,1-10H3/b38-21+,39-23+,40-25+,41-27+,42-29+,43-31+,44-33+,45-35+

InChI key

AFPLNGZPBSKHHQ-MEGGAXOGSA-N

 

安全信息

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

个人防护装备

Eyeshields, Gloves, type N95 (US)

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属性名称属性值
储存温度 Storage temp.-20°C低温冷冻
全球实时库存 Availability √美国St. Louis ≥ 30 | 欧洲Eur. ≥ 10 | 東京Tokyo ≥ 9 | 香港与北京 ≥ 30
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