科罗索酸,Corosolic acid from Lagerstroemia speciosa;≥98% (HPLC)

别名:2α,3β-2,3-二羟基熊-12-烯-28-酸;2α-羟基熊果酸;(2α,3β)-2,3-Dihydroxyurs-12-en-28-oic acid, 2α-Hydroxyursolic acid, Colosolic acid, Corosolic acid, Corsolic acid, Glucosol

Empirical Formula (Hill Notation): C30H48O4 CAS号: 4547-24-4 分子量: 472.70 MDL编号: MFCD06794973 PubChem化学物质编号: 329799816 NACRES: NA.25
制造商品牌: 西格玛 Sigma-Aldrich
货号(SKU): G0549
CAS号: 4547-24-4
MDL号: MFCD06794973
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¥2,665.06

说明

一般描述

Corosolic acid from Lagerstroemia speciosa is a pentacyclic triterpenoid found in a variety of plants, such as apples, basil, bilberries, cranberries, and prunes. It is a natural derivative of ursolic acid.
 

应用

Corosolic acid from Lagerstroemia speciosa has been used to study the inhibiting activity of ursolic acid and its derivative against colon cancer cells by causing degradation of β-catenins.[1]
 

生化/生理作用

Corosolic acid from Lagerstroemia speciose shows a variety of biological activities such as anti-proliferation, apoptosis, and anti-carcinogenic.[1] It exhibits an inhibiting effect on the post-challenge plasma glucose levels in humans.[2] Corosolic acid, due to its ability to improve glucose metabolism, has been touted to be used in the management of Type-2 Diabetes.[3] It improves hypertension, oxidative stress, and inflammation, thereby being a potential candidate to be used against atherosclerosis-related diseases.[4]
Triterpene phytochemical found in medicinal herbal extracts. Possesses antiatherosclerotic, antihyperlipidemic, antioxidant, antiinflammatory, antifungal, antiviral and antineoplastic activities.
 
 

属性

质量水平

检测方案

≥98% (HPLC)

形式

powder

溶解性

methanol: 1 mg/mL, clear, colorless

储存温度

2-8°C

SMILES string

O[C@H]1[C@H](O)C(C)(C)[C@@](CC[C@]2(C)[C@]3([H])CC=C4[C@@]2(C)CC[C@]5(C(O)=O)[C@@]4([H])[C@@H](C)[C@H](C)CC5)([H])[C@]3(C)C1

InChI

1S/C30H48O4/c1-17-10-13-30(25(33)34)15-14-28(6)19(23(30)18(17)2)8-9-22-27(5)16-20(31)24(32)26(3,4)21(27)11-12-29(22,28)7/h8,17-18,20-24,31-32H,9-16H2,1-7H3,(H,33,34)/t17-,18+,20-,21+,22-,23+,24+,27+,28-,29-,30+/m1/s1

InChI key

HFGSQOYIOKBQOW-ZSDYHTTISA-N

 

安全信息

储存分类代码

11 - Combustible Solids

WGK

WGK 3

商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 20 | 欧洲Eur. ≥ 16 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 20
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