盐酸阿霉素 [盐酸多柔比星]，Doxorubicin hydrochloride [DOX]；Pharmaceutical Secondary Standard; Certified Reference Material

别名：盐酸阿霉素标准品；阿霉素盐酸盐；多柔比星盐酸盐；羟基柔红霉素盐酸盐；14-羟基柔红霉素；14-羟基正定霉素；羟基正定霉素；亚得利亚霉素；亚德利亚霉素；DOX；Hydroxydaunorubicin hydrochloride

Empirical Formula (Hill Notation): C27H29NO11 · HCl CAS号: 25316-40-9 分子量: 579.98 Beilstein: 4229251 EC 号: 246-818-3 MDL编号: MFCD00077757 PubChem化学物质编号: 329823614

制造商品牌: 西格玛 Sigma-Aldrich , 色谱科 Supelco

货号（SKU）: PHR1789

CAS号: 25316-40-9

MDL号: MFCD00077757

签订合同 √ 正规发票 √ 技术支持 √ 质量保障 √ 全程可追溯 √

目录价.SKU-Variant

200mg

¥4,150.00

数量:

说明

盐酸多柔比星是一种蒽环类抗生素，以其广泛的抗癌活性而闻名。

一般描述

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Doxorubicin Hydrochloride is an anthracycline antibiotic, known for its broad range anti-cancer activities.

应用

This pharmaceutical secondary standard can also be used as follows:

Development of a reversed-phase high-performance liquid chromatographic (RP-HPLC) method combined with UV detection to determine doxorubicin hydrochloride in plasma samples
Electrochemical determination of doxorubicin by spinel-structured cobalt ferrite (CoFe₂O₄) modified carbon paste electrode in biological fluid and injection samples
Determination of doxorubicin hydrochloride in human plasma samples using a graphene quantum dots (GQDs) based electrochemical sensor
RP-HPLC method-based quantitative analysis of doxorubicin hydrochloride in vacuum foam dried formulations
Voltammetric determination of doxorubicin hydrochloride and dastinib using zinc oxide (ZnO) nanoparticle/1-butyl-3-methylimidazolium tetra-fluoroborate modified carbon paste electrode (ZnO-NPs/BMTFB/CPE) in their combined injection samples

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

附注

To see an example of a Certificate of Analysis for this material enter LRAB3692 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

属性

等级

certified reference material
pharmaceutical secondary standard

质量水平

300

Agency

traceable to BP 990
traceable to Ph. Eur. D2975000
traceable to USP 1225703

形式

powder

CofA

current certificate can be downloaded

包装

pkg of 200 mg

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

216 °C (dec.) (lit.)

application(s)

pharmaceutical (small molecule)

储存温度

-10 to -25°C

SMILES string

Cl[H].COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(=O)CO

InChI

1S/C27H29NO11.ClH/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34;/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3;1H/t10-,13-,15-,17-,22+,27-;/m0./s1

InChI key

MWWSFMDVAYGXBV-RUELKSSGSA-N

Gene Information

human ... TOP2A(7153)

安全信息

象形图

GHS07,GHS08

警示用语：

Danger

危险声明

H302 - H340 - H350 - H360FD

预防措施声明

P202 - P264 - P270 - P280 - P301 + P312 - P308 + P313

危险分类

Acute Tox. 4 Oral - Carc. 1B - Muta. 1B - Repr. 1B

储存分类代码

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

商品规格

属性名称	属性值
储存温度 Storage temp.	-20°C低温冷冻
全球实时库存 Availability √	美国St. Louis ≥ 30 \| 欧洲Eur. ≥ 10 \| 東京Tokyo ≥ 9 \| 香港与北京 ≥ 30

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