白术内酯I，Atractylenolide I；≥98% (HPLC)

Atractylenolide I is one of the active ingredients of Rhizoma Atractylodes macrocephala which is obtained from the dried root and stem of Atractylodes Macrocephala Koidz. It is a sesquiterpene compound of hydrophobic nature.[1][2][3]

 

Atractylenolide I is a phytochemical that may be used to study its anti-inflammatory and anti-angiogenesis activities. Atractylenolide I may be used and studied as a postitive modulator of GABA-induced chloride currents I(GABA) and as an inhibitor of aromatases. Atractylenolide I may be used as a reference material in assays to detect its presence in plant root extracts and biological milieu such as plasma.

 

Atractylenolide I has been reported to have an anti-inflammatory activity due to its inhibitory effect on tumor necrosis factor-α (TNF-α) and the production of nitric oxide (NO).[1] It also shows anti-cancer nature, thereby being used in the management of gastric cancer cachexia symptoms.[4] Additionally, it has anti-angiogenic[2], pro-oxidative and cytotoxic characteristics.[3]

Phytochemical from Traditional Chinese Medicine herbal preparations. Atractylenolide I is an anti-inflammatory that is reported to inhibit angiogenesis.