| Catalogue Number | P689410 |
| Chemical Name | Polythiazide |
| Synonyms | 6-Chloro-3,4-dihydro-2-methyl-3-[[2,2,2-trifluoroethyl)thio]methyl]-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-Dioxide; (±)-Nephril; (±)-Polythiazide; 6-Chloro-3,4-dihydro-2-methyl-7-sulfamoyl-3-(2,2,2-trifluoroethylthiomethyl)-2H-1,2,4-benzothiadiazine 1,1-Dioxide; Drenusil; NSC 108161; Nephril; P 2525; Renese; |
| CAS Number | 346-18-9 |
| Molecular Formula | C₁₁H₁₃ClF₃N₃O₄S₃ |
| Appearance | White to Off-White Solid |
| Melting Point | 211 - 214°C |
| Molecular Weight | 439.88 |
| Storage | Refrigerator |
| Solubility | DMSO (Slightly), Methanol (Slightly, Heated) |
| Category | Standards; Pharmaceutical/API Drug Impurities/Metabolites; |
| Applications | Polythiazide is a thiazide diuretic. Polythiazide is used in the treatment of hypertension as well as nephrotic syndrome, cirrhosis of the liver, and nutritional edema. |
| References | Kaur, J. et al.: J. Ind. Med. Assoc., 48, 13, (1967); Lund-Johansen, P.: Acta Med. Scand., 187, 509 (1970); O'Brien, E.T. et al.: Br. Heart J., 34, 1042 (1972); |
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