氨曲南,Aztreonam;analytical standard

别名:氨曲南标准品;噻肟单酰胺菌素;SQ-26,776;2S-2α,3β(Z)-2-1-(2-氨基-4-噻唑基)-2-(2-甲基-4-氧代-1-磺基-3-氮杂环丁烷)氨基-2-氧代亚乙基氨基氧代-2-甲基丙酸;2S-2α,3β(Z)-2-1-(2-Amino-4-thiazolyl)-2-(2-methyl-4-oxo-1-sulfo-3-azetidinyl)amino-2-oxoethylideneaminooxy-2-methylpropanoic acid, 2-(Z)-1-(2-Amino-4-thiazolyl)-2-(2S,3S)-2-methyl-4-oxo-1-sulfo-3-azetidinylamino-2-oxoethylideneaminooxy-2-methyl-propanoic acid

Empirical Formula (Hill Notation): C13H17N5O8S2 CAS号: 78110-38-0 分子量: 435.43 EC 号: 278-839-9 MDL编号: MFCD00072145 PubChem化学物质编号: 329770905
货号(SKU): A6848
CAS号: 78110-38-0
MDL号: MFCD00072145
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¥1,976.00

说明

一般描述

Aztreonam belongs to the group of monocyclic β-lactam antibiotics, isolated from Chromobacterium violaceum. It is used against gram-negative bacterial infections, such as infections of the bladder, kidneys, bone, and urinary tract. It acts by binding to the penicillin-binding protein-3 (PBP3) and inhibiting the synthesis of bacterial cell walls causing cell lysis and death.
 

应用

The analytical standard can be used as follows:
  • Determination of aztreonam in two simulated lung fluid solutions― artificial lysosomal fluid and gamble solution by a UV spectroscopic method
  • Multi-residue analysis of eight β-lactams by ultra-high performance liquid chromatography (UHPLC) combined with a photo-diode array (PDA) detector in human plasma & serum samples
  • Simultaneous quantitative analysis of nine β-lactams by UHPLC along with tandem mass spectrometry (MS/MS) in human plasma samples

其他说明

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
 
 

属性

等级

analytical standard

质量水平

形式

powder or crystals

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

SMILES string

C[C@H]1[C@H](NC(=O)\C(=N/OC(C)(C)C(O)=O)c2csc(N)n2)C(=O)N1S(O)(=O)=O

InChI

1S/C13H17N5O8S2/c1-5-7(10(20)18(5)28(23,24)25)16-9(19)8(6-4-27-12(14)15-6)17-26-13(2,3)11(21)22/h4-5,7H,1-3H3,(H2,14,15)(H,16,19)(H,21,22)(H,23,24,25)/b17-8-/t5-,7-/m0/s1

InChI key

WZPBZJONDBGPKJ-VEHQQRBSSA-N

 

安全信息

储存分类代码

11 - Combustible Solids

WGK

WGK 2

个人防护装备

Eyeshields, Gloves, type N95 (US)

商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 20 | 欧洲Eur. ≥ 16 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 20
商品标签 [tags]