槐角苷,Sophoricoside;≥98% (HPLC)

别名:槐花甙;槐甙;5,7-二羟基-4-葡萄糖基氧基异黄酮; 染料木黄酮-4′-O-葡萄糖苷;5′,7′-Dihydroxy-4′-glucosyloxyisoflavone;Genistein-4′-O-glucoside

Empirical Formula (Hill Notation): C21H20O10 CAS号: 152-95-4 分子量: 432.38 PubChem化学物质编号: 329825016 NACRES: NA.25
制造商品牌: 西格玛 Sigma-Aldrich
货号(SKU): SMB00438
CAS号: 152-95-4
MDL号: MFCD01075138
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¥1,321.55

说明

一般描述

Sophoricoside is an isoflavone glycoside found in the fruit of Sophora japonica.[1] It is a structural isomer of genistin.[2]
 

生化/生理作用

Sophoricoside (SOP) improves lipopolysaccharides (LPS)-induced acute lung injury (ALI) in mice by activating the adenosine monophosphate-activated protein kinase (AMPK)/nuclear factor erythroid 2-related factor 2 (Nrf2) signaling pathway. It also improves contact dermatitis by inhibiting the nuclear factor-kappa B (NF-κB) pathway in B cells in mice model.
Sophoricoside elicits anti-cancer, immunosuppressive, and anti-inflammatory activities.[1] It inhibits proinflammatory cytokine production in human mast cells and has the potential to treat allergic inflammation diseases.[1]
 
 

属性

质量水平

检测方案

≥98% (HPLC)

形式

powder

储存温度

2-8°C

SMILES string

OC1=CC(O)=C(C(C(C2=CC=C(O[C@H]3O[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]3O)C=C2)=CO4)=O)C4=C1

InChI

1S/C21H20O10/c22-7-15-18(26)19(27)20(28)21(31-15)30-11-3-1-9(2-4-11)12-8-29-14-6-10(23)5-13(24)16(14)17(12)25/h1-6,8,15,18-24,26-28H,7H2/t15-,18-,19+,20-,21-/m0/s1

InChI key

ISQRJFLLIDGZEP-JDCPMNFLSA-N

 

安全信息

储存分类代码

11 - Combustible Solids

WGK

WGK 3

商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 20 | 欧洲Eur. ≥ 16 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 20
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