支链聚乙烯亚胺，Polyethylenimine, branched [PEI]；average Mw ~800 by LS, average Mn ~600 by GPC

Polyethyleneimine is a hydrophilic polymerwidely used as a non-viral synthetic vector for invivo delivery of therapeutic nucleic acids. Owing to its excellentphysicochemical properties, it is applied in many fields like the separationand purification of proteins, carbon dioxide absorption, drug carriers,effluent treatment, and biological labels.

 

洗涤剂、粘合剂、水处理、油墨、染料、化妆品和造纸业、助粘剂、层压底漆、固色剂、絮凝剂、阳离子分散剂、稳定剂、表面活性剂、螯合剂以及醛类和氧化物清除剂。

Branched PEI can be used as a precursor to synthesize conjugated polyplexes for efficient gene transfection. Conjugation of PEI with Jeffamine polyether and guanidinylation of the amino groups of PEI reduce the cytotoxicity of the polyplexes and protect them from aggregation in the presence of serum proteins.

Bamboo charcoal impregnated with PEI can be used as a CO₂ adsorbent. Numerous amino groups present in PEI can react with CO₂ due to acid-alkali interaction and enhance the adsorption capacity of bamboo charcoal.

It can also be used to prepare cross-linked water-soluble polymers with high coordination capabilities towards organic drug molecules.

 

支化聚合物